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Merck

O-025

Supelco

Oxcarbazepine solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

実験式(ヒル表記法):
C15H12N2O2
CAS番号:
分子量:
252.27
EC Number:
UNSPSCコード:
41116107
NACRES:
NA.24

グレード

certified reference material

品質水準

フォーム

liquid

特徴

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

メーカー/製品名

Cerilliant®

濃度

1.0 mg/mL in acetonitrile

テクニック

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

アプリケーション

clinical testing

フォーマット

single component solution

保管温度

−20°C

SMILES記法

NC(=O)N1c2ccccc2CC(=O)c3ccccc13

InChI

1S/C15H12N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8H,9H2,(H2,16,19)

InChI Key

CTRLABGOLIVAIY-UHFFFAOYSA-N

詳細

Oxcarbazepine, marketed under the trade name Trileptal®, is an anticonvulsant developed and prescribed for treatment of epilepsy. In recent years, Oxcarbazepine has shown efficacy in treatment of mood disorders. This certified solution standard is suitable as starting material for the preparation of calibrators and controls in oxcarbazepine testing by GC/MS or LC-MS/MS.

アプリケーション


  • Quantitative analysis for therapeutic monitoring: Oxcarbazepine solution is utilized in liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods for the quantitative analysis of drug levels in patients undergoing epilepsy treatment. This approach aids in therapeutic drug monitoring, ensuring drug efficacy and safety (Johnson-Davis and Thomas, 2024).

  • Advanced detection techniques: Research integrates Raman spectroscopy and convolutional neural networks for the detection of antiepileptic drug concentrations, including Oxcarbazepine. This technology enhances the precision of drug measurement, vital for managing and controlling seizures in neurological disorders (Fu et al., 2023).

  • Environmental impact studies: Studies on the degradation of Oxcarbazepine by bromate in water under sunlight irradiation provide critical data on the environmental behavior of this pharmaceutical. Understanding its environmental breakdown helps in assessing the ecological impact and designing better waste management strategies (Sun et al., 2023).


法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Trileptal is a registered trademark of Novartis Corporation

ピクトグラム

FlameExclamation mark

シグナルワード

Danger

危険有害性情報

危険有害性の分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

保管分類コード

3 - Flammable liquids

WGK

WGK 2

引火点(°F)

35.6 °F - closed cup

引火点(℃)

2 °C - closed cup


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

毒物及び劇物取締法

劇物

消防法

第4類:引火性液体
第一石油類
危険等級II
非水溶性液体

労働安全衛生法名称等を表示すべき危険物及び有害物

名称等を表示すべき危険物及び有害物

労働安全衛生法名称等を通知すべき危険物及び有害物

名称等を通知すべき危険物及び有害物

Jan Code

O-025-1ML:4548173346106
O-025-CC:


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試験成績書(COA)

Lot/Batch Number

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以前この製品を購入いただいたことがある場合

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文書ライブラリにアクセスする

A Vasudev et al.
The Cochrane database of systematic reviews, (1)(1), CD005171-CD005171 (2008-02-07)
Some studies have suggested that oxcarbazepine has a role in preventing episode recurrence in bipolar affective disorder. This review attempted to investigate the existing evidence from randomised controlled trials for its use in the maintenance treatment of this illness. To
Barbara R Sommer et al.
Expert opinion on drug safety, 6(2), 133-145 (2007-03-21)
Few controlled studies are available to guide the clinician in treating potentially assaultive elderly individuals with psychiatric disorders. Safety concerns limit the use of benzodiazepines and antipsychotic medications in the elderly individual, making anticonvulsants an attractive alternative. This paper reviews
Ekaterine Popova et al.
Expert review of neurotherapeutics, 7(6), 617-626 (2007-06-15)
Oxcarbazepine is an antiepileptic drug that has been approved by the US FDA and is indicated for use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults and children aged over 4 years. The aim of
Régis Bouquié et al.
Therapie, 65(1), 61-65 (2010-03-09)
Oxcarbazepine is an analogue of carbamazepine, used for the treatment of partial seizure with or without secondary generalization. The two forms R and S of the mono-hydroxylated derivatives (MHD) are responsible for most of the anti-convulsant activity and it is
Gaetano Zaccara et al.
Seizure, 22(7), 528-536 (2013-04-30)
Analysis of overall tolerability and neurological adverse effects (AEs) of eslicarbazepine acetate (ESL), lacosamide (LCM) and oxcarbazepine (OXC) from double-blind, placebo-controlled trials. Indirect comparisons of patients withdrawing because of AEs, and the incidence of some vestibulocerebellar AEs between these three

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