P-077

Propofol-D₁₇ solution

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₁₂D₁₇HO
• CAS番号: 1261393-54-7
• 分子量: 195.38
• EC Number: 200-659-6
• MDL番号: MFCD10001682
• UNSPSCコード: 41116107
• PubChem Substance ID: 329820054
• NACRES: NA.24

特性

• グレード: certified reference material
• 品質水準: 300
• フォーム: liquid
• 特徴: Snap-N-Spike^®/Snap-N-Shoot^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• 濃度: 100 μg/mL in methanol
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: forensics and toxicology
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: OC1=C(C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C([2H])=C([2H])C([2H])=C1C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
• InChI: 1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3/i1D3,2D3,3D3,4D3,5D,6D,7D,8D,9D
• InChI Key: OLBCVFGFOZPWHH-ACWNEFEHSA-N

詳細

詳細

Propofol, also known as Diprivan^®, is a short-acting, hypnotic drug intravenously administered for the induction and maintenance of general anesthesia and sedation. This internal standard is suitable for a variety of uses including forensic and forensic toxicology analysis, isotope dilution methods, calibrator preparation, and drug monitoring in plasma or whole blood.

アプリケーション

• Propofol-D₁₇ in forensic analysis: Propofol-D₁₇ was utilized to confirm testimonial evidence in serial homicide cases through drug detection in decomposed cadavers, demonstrating its value in complex forensic scenarios (Ottaviano et al., 2021).


• Pharmacokinetic studies with Propofol-D₁₇: A sensitive LC-APCI-MS/MS method was developed using Propofol-D₁₇ to quantify propofol in a bioequivalence study among healthy Chinese subjects, enhancing understanding of its pharmacokinetics (Tang et al., 2020).


• Evaluation of analytical methods using Propofol-D₁₇: Comparative analysis of LC-MS/MS and GC-MS for propofol detection highlights Propofol-D₁₇′s role in improving analytical procedures for forensic and clinical toxicology (Vaiano et al., 2015).

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Diprivan is a registered trademark of Abraxis Bioscience, Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 49.5 °F - closed cup
• 引火点(℃): 9.7 °C - closed cup