S-010

シルデナフィル 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₂₂H₃₀N₆O₄S
• CAS番号: 139755-83-2
• 分子量: 474.58
• EC Number: 200-659-6
• MDL番号: MFCD00867528
• UNSPSCコード: 41116107
• PubChem Substance ID: 329824411
• NACRES: NA.24

特性

• グレード: certified reference material
• 品質水準: 300
• フォーム: liquid
• 特徴: Snap-N-Spike^®/Snap-N-Shoot^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• 濃度: 1.0 mg/mL in methanol
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: pharmaceutical (small molecule)
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: O=C1NC(C2=C(OCC)C=CC(S(=O)(N3CCN(C)CC3)=O)=C2)=NC4=C1N(C)N=C4CCC
• InChI: 1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)
• InChI Key: BNRNXUUZRGQAQC-UHFFFAOYSA-N
• 遺伝子情報: human ... PDE5A(8654)

詳細

詳細

Sildenafil is a treatment for erectile dysfunction and pulmonary arterial hypertension. Sold under the trade name Viagra^®, sildenafil has a history of abuse, including by athletes as a performance enhancing drug. This Certified Spiking Solution^® is applicable for use in urine drug testing, sports testing, clinical toxicology or forensic analysis by LC-MS/MS or GC/MS.

アプリケーション

• Effect of topical sildenafil on wound healing and oxidative stress in rats: This study investigates the application of sildenafil in a topical solution form to enhance wound healing and reduce oxidative stress in a rat model, providing insights into its potential therapeutic applications (Tunc and Ercan, 2024).


• The Physicochemical Compatibility of Sildenafil Injection with Parenteral Medications: Research assesses the compatibility of sildenafil solution when combined with various parenteral medications used in neonatal intensive care, suggesting its safe and effective integration for clinical use (De Silva et al., 2024).


• Changes in Pulmonary Vascular Resistance and Obstruction Score Following Acute Pulmonary Embolism: This study uses sildenafil in a model of acute pulmonary embolism in pigs to evaluate its effects on pulmonary vascular resistance and obstruction, highlighting its potential in managing this condition (Merit et al., 2024).

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Viagra is a registered trademark of Pfizer, Inc.

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• ターゲットの組織: Eyes,Central nervous system
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 2
• 引火点(°F): 49.5 °F - closed cup
• 引火点(℃): 9.7 °C - closed cup