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詳細
Modified amino acids are inhouse manufactured amino acid derivatives with specific properties enabling the intensification of cell culture processes.
Together with the companion product Phospho-L-Tyrosine disodium Salt disodium salt, the new modified amino acid S-Sulfocysteine sodium salt can be used as replacement for cysteine to generate highly concentrated, neutral pH feeds. Both modified amino acids eliminate the need for alkaline feeds, which are normally applied to ensure solubility and stability of the unmodified amino acids tyrosine and cysteine.
Together with the companion product Phospho-L-Tyrosine disodium Salt disodium salt, the new modified amino acid S-Sulfocysteine sodium salt can be used as replacement for cysteine to generate highly concentrated, neutral pH feeds. Both modified amino acids eliminate the need for alkaline feeds, which are normally applied to ensure solubility and stability of the unmodified amino acids tyrosine and cysteine.
Our SAFC® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.
M-Clarity Program
As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
M-Clarity Program
As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.
Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
特徴および利点
- Reduced complexity in fed-batch process
- High concentrations of modified cysteine in main feeds at neutral pH
- Prevention of caustic shocks in the bioreactor due to high pH feeds
- More convenient preparation process with less contamination risks
- Reduction of recombinant protein fragmentation and decrease in trisulfide bond content
- Higher feed stability at room temperature
関連事項
法的情報
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
1371161000:
1371165000:
137116-RSAMPLE:
1371160000:
137116-BULK:
1371160100:
試験成績書（COA）
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