164610

p-Aminophenylmercuric Acetate

An organomercurial agent used for the activation of latent MMPs in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.

• 別名: p-Aminophenylmercuric Acetate, APMA
• 実験式（ヒル表記法）: C₈H₉HgNO₂
• CAS番号: 6283-24-5
• 分子量: 351.75
• MDL番号: MFCD00007820
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥90% (HPLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: yellow
• 溶解性: 0.1 M NaOH: 10 mg/mL; DMSO: 10 mg/mL
• 輸送温度: ambient
• 保管温度: 10-30°C
• InChI: 1S/C6H6N.C2H4O2.Hg/c7-6-4-2-1-3-5-6;1-2(3)4;/h2-5H,7H2;1H3,(H,3,4);/q;;+1/p-1
• InChI Key: RXSUFCOOZSGWSW-UHFFFAOYSA-M

詳細

詳細

An organomercurial agent used for the activation of latent MMPs in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.

An organomercurial agent used for the activation of latent matrix metalloproteinases (MMPs) in vitro. Acts by facilitating the loss of the enzyme propeptide domain through an autolytic cleavage known as the cysteine switch.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Activation of latent MMPs in vitro

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Highly Toxic (H)

再構成

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 1 month at 4°C.

その他情報

Chen, J.-M., et al. 1991. J. Biol. Chem. 266, 5113.
Marcy, A.I., et al. 1991. Biochemistry30, 6476.
Stricklin, G.P., et al. 1983. Biochemistry22, 61.

Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS06,GHS08,GHS09
• シグナルワード: Danger
• 危険有害性情報: H300 + H310 + H330,H373,H410
• 注意書き: P262 - P264 - P273 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• 危険有害性の分類: Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
• 保管分類コード: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable