345752

Ganglioside GD₃, Disialo, Diammonium Salt, Bovine Buttermilk

Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma.

• 別名: Ganglioside GD₃, Disialo, Diammonium Salt, Bovine Buttermilk, Neu5Acα2,8Neu5Acα2,3Galβ1,4Glcβ1,1 Ceramide, 2NH₄
• 実験式（ヒル表記法）: C₇₀H₁₂₃N₃O₃₀ · 2NH₄
• 分子量: 1522.80
• UNSPSCコード: 12352211
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (TLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 色: white
• 溶解性: water: 1 mg/mL; chloroform/methanol (2:1): soluble
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

Has been characterized as one of the most important tumor-specific antigens in individuals with malignant melanoma. Reported to disrupt mitochondrial transmembrane potential and induce apoptosis in tumor cells by a caspase-independent mechanism. Antibodies to GD₃ can induce partial remission of tumor growth in animals and in humans via enhancement of cytotoxic and proliferative responses of lymphocytes. M.W. 1577.0 (based on tricosanoyl - 23:0).

警告

Toxicity: Irritant (B)

その他情報

DeMaria, R., et al. 1997. Science 277, 1652.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable