345744

Ganglioside GT_1b, Trisialo, Triammonium Salt, Bovine Brain

Inhibits Con A-stimulated mitogenesis in murine T cells.

• 別名: Ganglioside GT_1b, Trisialo, Triammonium Salt, Bovine Brain, Neu5Acα2,3Galβ1,3GalNAcβ1,4(Neu5Acα2,8Neu5Acα2,3)Galβ1,4Glcβ1,1 Ceramide, 3NH₄
• 実験式（ヒル表記法）: C₉₅H₁₆₂N₅O₄₇ · 3NH₄
• 分子量: 2180.42
• UNSPSCコード: 12352211
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (TLC)
• フォーム: lyophilized
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 溶解性: ethanol: soluble; methanol: soluble
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

Inhibits Con A-stimulated mitogenesis in murine T cells. Lymphocyte marker in cancer patients. Readily converted to GD_1b-disialoganglioside by bacterial and other mammalian neuraminidases without detergent or bile salts.

M.W. 2180.5 (based on stearoyl - 18:0).

Trisialoganglioside prepared from bovine gray matter. Readily converted to GD_1b-disialoganglioside by bacterial and mammalian sialidases without detergent or bile salts. Inhibits mitogenesis in concanavalin A-stimulated murine T-cells. Lymphocyte marker in cancer patients.



Note: This product is not to be used for animal treatment, in vivo research or in any other contact procedure with livestock.

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Inhibits Con A-stimulated mitogenesis in murine T cells

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Irritant (B)

調製ノート

For use in aqueous systems, dissolve in a small amount of ethanol and then sonicate in buffer or medium, or dissolve the dried sample directly in aqueous buffers by sonication. Solutions can be filter sterilized.

再構成

Following reconstitution, store in the refrigerator(4°C). Stock solutions are stable for up to 6 months at 4°C.

その他情報

Hakomori, S. 1985. Cancer Res.45, 2405.
Momoi, T., et al. 1976. Biochim. Biophys. Acta441, 488.
Warren, L. 1959. J. Biol. Chem.234, 1971.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable