444287

MMP-13, Human, Recombinant, Active

• 別名: Matrix metalloproteinase 13
• UNSPSCコード: 12352202
• NACRES: NA.77

特性

• フォーム: liquid
• 品質水準: 100
• 比活性: ≥50 mU/mg protein
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; avoid repeated freeze/thaw cycles
• 輸送温度: wet ice
• 保管温度: −70°C

詳細

詳細

Recombinant, human MMP-13. MMP-13 is a collagenase-3 enzyme that degrades a range of extracellular matrix proteins, including collagen types I, II, III, IV, IX, X, and XIV, gelatin, aggrecan, perlecan and fibronectin. It is distinguished from other human collagenases by the fact that it effectively degrades type II collagen. The importance of MMP-13 is further strengthened by reports that it is a biomarker for poor prognosis in many carcinomas and other type of cancers.

包装

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

単位の定義

One unit is defined as the amount of APMA-activated enzyme that will hydrolyze 1µmol MCA-Pro-Leu-Lys-Gly-Leu-DPA-Ala-Arg-NH₂ (Cat. No. 03-32-5032) at 37°C, pH 7.5.

物理的形状

In 50 mM HEPES, 10 mM CaCl₂, 20% glycerol, 0.005% Brij^® 35 Detergent, pH 7.5. APMA-free.

再構成

Following initial thaw, aliquot and freeze (-70°C).

その他情報

Freije, M.P.S., et al. 1994. J. Biol. Chem.269,16766.

法的情報

Brij is a registered trademark of Croda International PLC

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable