557450

Ruthenium Red

A blocker of transmembrane Ca²⁺ fluxes (IC₅₀ = 7 µM) that attenuates capsaicin-induced cation channel opening.

• 別名: Ruthenium Red, Ammoniated Ruthenium Oxychloride, RR
• 化学式: [(NH₃)₅RuORu(NH₃)₄ORu(NH₃)₅]Cl₆
• CAS番号: 12790-48-6
• MDL番号: MFCD00270912
• UNSPSCコード: 12352200
• NACRES: NA.77

特性

• 品質水準: 100
• フォーム: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated
• 色: red-black
• 溶解性: ammonia: soluble; water: soluble
• 輸送温度: ambient
• 保管温度: 10-30°C

詳細

詳細

A blocker of transmembrane Ca²⁺ fluxes (IC₅₀ = 7 µM) that attenuates capsaicin-induced cation channel opening. Inhibits Ca²⁺-induced Ca²⁺ release from ryanodine-sensitive intracellular Ca²⁺ stores. Inhibits K⁺-stimulated catecholamine secretion (IC₅₀ = 6 µM).

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Blocker of transmembrane Ca2+ fluxes

Product does not compete with ATP.

Reversible: no

Target IC₅₀: 7 µM in blocking transmembrane Ca2+ fluxes; 6 µM inhibiting K+-stimulated catecholamine secretion

警告

Toxicity: Harmful (C)

その他情報

Merck Index 13, 8379.
Phillippe, M. and Basa, A. 1996. Biochem. Biophys. Res. Commun. 221, 656.
Buratti, R., et al. 1995. Biochem. Biophys. Res. Commun. 213, 1082.
Hamilton, M.G. and Lundy, P.M. 1995. J. Pharmacol. Exp. Ther. 273, 940.
Gomis, A., et al. 1994. Biochem. Pharmacol. 47, 225.
Stjame, P., et al. 1994. Acta Otolaryngol. 114, 651.
Ma, J. 1993. J. Gen. Physiol.102, 1031.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302
• 注意書き: P264 - P270 - P301 + P312 - P501
• 危険有害性の分類: Acute Tox. 4 Oral
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable