561300

E-Selectin, Human, Recombinant, CHO Cells

• 別名: CD62E, ELAM-1
• UNSPSCコード: 12352202
• NACRES: NA.77

特性

• アッセイ: ≥95% (SDS-PAGE)
• 品質水準: 100
• 形状: lyophilized
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 不純物: <1 EU/μg Endotoxin (EU/μg of E-Selectin)
• 輸送温度: wet ice
• 保管温度: −20°C

詳細

詳細

Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands such as SLe^x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.

Recombinant, human E-selectin consisting of 535 amino acids minus the transmembrane and cytoplasmic domains expressed in CHO cells. This glycoprotein is transiently expressed on vascular endothelial cell surfaces where it is able to bind to ligands, such as sialyl Lewis x found on leukocytes. This initial binding event is followed by a second interaction involving ICAM and VCAM-1 that leads to vascular penetration and leukocyte invasion into the extracellular matrix tissue.

生物化学的／生理学的作用

Shown to bind to E-selectin ligands on U937 cells.

警告

Toxicity: Standard Handling (A)

物理的形状

Lyophilized from Dulbecco′s PBS with stabilizer.

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.

Reconstitute to 1 mg/ml with sterile H₂O.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2