8.51028

Bis-Boc-amino-oxyacetic acid

Novabiochem^®

• 別名: Bis-Boc-amino-oxyacetic acid, Boc ₂-Aoa-OH
• 実験式（ヒル表記法）: C₁₂H₂₁NO₇ · xH₂O
• 分子量: 291.30 (anhydrous basis)
• UNSPSCコード: 12352209
• NACRES: NA.22

特性

• 品質水準: 200
• 製品種目: Novabiochem^®
• アッセイ: ≥97% (TLC)
• 形状: powder
• 反応適合性: reagent type: ligand
• メーカー／製品名: Novabiochem^®
• アプリケーション: peptide synthesis
• 保管温度: 2-8°C

詳細

詳細

This reagent can be used to introduce a hydroxylamine functionality to N-terminal or side-chain amino groups. Hydroxylamine-labeled peptides prepared in this manner can be ligated in aqueous solution at pH 3.5 to aldehyde-containing peptides via oxime formation. This bis-protected derivative eliminates oligomer formation which can occur with mono-protected hydroxylamine reagents as a result of double acylation. Coupling of this derivative should be done using an OSu ester.

Literature references

^[1] J. C. Spetzler & T. Hoeg-Jensen (2001) J. Peptide Sci., 7, 537.

関連事項

Replaces: 01-63-0129

アナリシスノート

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 97 %
Water (K. F.): 3.0 - 8.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法的情報

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3