MAB1587
Anti-Glutamate Transporter Antibody, neuronal, clone 4D6.2
clone 4D6.2, Chemicon®, from mouse
別名:
EAAT3
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About This Item
UNSPSCコード:
12352203
eCl@ss:
32160702
NACRES:
NA.41
クローン:
4D6.2, monoclonal
application:
IHC
WB
WB
化学種の反応性:
rat
テクニック:
immunohistochemistry: suitable
western blot: suitable
western blot: suitable
citations:
8
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由来生物
mouse
品質水準
抗体製品の状態
purified immunoglobulin
抗体製品タイプ
primary antibodies
クローン
4D6.2, monoclonal
化学種の反応性
rat
メーカー／製品名
Chemicon®
テクニック
immunohistochemistry: suitable
western blot: suitable
アイソタイプ
IgG1
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... SLC1A1(6505)
特異性
Glutamate Transporter EAAC1.
Based on protein sequence the antibody is expected to react with mouse, bovine and rabbit.
Based on protein sequence the antibody is expected to react with mouse, bovine and rabbit.
免疫原
C-terminus peptide (KDKSDTISFTQTSQF) (Catalog Number AG372).
アプリケーション
Research Category
ニューロサイエンス
ニューロサイエンス
Research Sub Category
神経伝達物質及び受容体
神経伝達物質及び受容体
Anti-Glutamate Transporter Antibody, neuronal, clone 4D6.2 is an antibody against Glutamate Transporter for use in IH & WB.
Western blot: 1-2 μg/mL
Immunohistochemistry: 1-2 μg/mL
Optimal working dilutions must be determined by end user.
EAAC1 is approximately 66-70kDa; the protein can form homomultimers during preparation as well, thus often times large 200-220kDa bands can also be seen.
Immunohistochemistry: 1-2 μg/mL
Optimal working dilutions must be determined by end user.
EAAC1 is approximately 66-70kDa; the protein can form homomultimers during preparation as well, thus often times large 200-220kDa bands can also be seen.
物理的形状
Format: Purified
Purified immunoglobulin. Liquid in 0.02M Phosphate buffer, 0.25M NaCl, pH 7.6 with 0.1% sodium azide.
保管および安定性
Maintain at 2-8°C for up to six months.
その他情報
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法的情報
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 2
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
MAB1587:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Clozapine-induced reduction of glutamate transport in the frontal cortex is not mediated by GLAST and EAAC1.
M Melone et al.
Molecular psychiatry, 8(1), 12-13 (2003-01-31)
Bárbara Coimbra et al.
Nature communications, 10(1), 4138-4138 (2019-09-14)
The laterodorsal tegmentum (LDT) is associated with reward considering that it modulates VTA neuronal activity, but recent anatomical evidence shows that the LDT also directly projects to nucleus accumbens (NAc). We show that the majority of LDT-NAc inputs are cholinergic
M C Medrano et al.
British journal of pharmacology, 169(8), 1781-1794 (2013-05-04)
Excitatory amino acid transporters (EAATs) in the CNS contribute to the clearance of glutamate released during neurotransmission. The aim of this study was to explore the role of EAATs in the regulation of locus coeruleus (LC) neurons by glutamate. We
Han-Byeol Kim et al.
Cell death discovery, 6, 73-73 (2020-08-21)
Neonatal maternal separation (NMS), as an early-life stress (ELS), is a risk factor to develop emotional disorders. However, the exact mechanisms remain to be defined. In the present study, we investigated the mechanisms involved in developing emotional disorders caused by
Han-Byeol Kim et al.
Molecular brain, 13(1), 153-153 (2020-11-15)
Excitatory amino acid carrier 1 (EAAC1) is an important subtype of excitatory amino acid transporters (EAATs) and is the route for neuronal cysteine uptake. CoCl2 is not only a hypoxia-mimetic reagent but also an oxidative stress inducer. Here, we found
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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