MABT78

Anti-mouse CD44 (H-CAM) Antibody, clone KM201

clone KM201, from rat

• 別名: CD44 antigen (homing function and Indian blood group system), CDw44 antigen, HCAM, H-CAM, HUTCH-1, Phagocytic glycoprotein I, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, Heparan sulfate proteoglycan, Hermes antigen, Hyalu
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rat
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: KM201, monoclonal
• 化学種の反応性: mouse
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG1κ
• NCBIアクセッション番号: NP_001034240
• UniProtアクセッション番号: P15379
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CD44(960)

詳細

詳細

CD44, also known as H-CAM is a distinct adhesion molecule that, with its 13 known isoforms, comprises a family of transmembrane glycoproteins involved in a wide variety of significant biological processes. Members belonging to this family are involved in apoptosis, migration, metastasis, tumor progression, lymphocyte homing, and the attachment of hematopoietic cells to stromal cells. CD44 is the primary cell surface receptor for hyaluronic acid (HA), and is also a notable target for WNT signaling within the intestinal mucosa. Recent studies have used CD44 marker as a means to isolate different cancer stem cells (CSC) such as; colorectal CSC, pancreatic CSC, and prostate CSC.

特異性

The antibody recognizes CD44 near the hyaluronate binding domain.

免疫原

Epitope: Near the hyaluronate binding domain

Mouse bone marrow-derived stromal cells

アプリケーション

Research Category
細胞骨格

幹細胞研究

Research Sub Category
接着分子（CAM）

造血幹細胞

Detect mouse CD44 (H-CAM) using this Anti-mouse CD44 (H-CAM) Antibody, clone KM201 validated for use in FC.

品質

Evaluated by Flow Cytometry in mouse bone marrow cells.

Flow Cytometry Analysis: 0.1 µg of this antibody detected CD44 in mouse bone marrow cells.

ターゲットの説明

86 kDa calculated

関連事項

Replaces: CBL1308

物理的形状

Protein G

Format: Purified

Purified rat monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine, pH 7.4, 150 mM NaCl, with 0.05% sodium azide.

保管および安定性

Stable for 1 year at 2-8°C from date of receipt.

アナリシスノート

Control
Mouse bone marrow cells

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable