34002

(S)-(−)-スルピリド

VETRANAL^®, analytical standard

• 別名: (S)-5-アミノスルホニル-N-[(1-エチル-2-ピロリジニル)メチル]-2-メトキシベンズアミド, レボスルピリド
• 実験式（ヒル表記法）: C₁₅H₂₃N₃O₄S
• CAS番号: 23672-07-3
• 分子量: 341.43
• MDL番号: MFCD00055220
• UNSPSCコード: 41116107
• PubChem Substance ID: 329754747
• NACRES: NA.24

特性

• グレード: analytical standard
• 品質水準: 100
• 製品種目: VETRANAL^®
• シェルフライフ: limited shelf life, expiry date on the label
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 183-186 °C (lit.)
• アプリケーション: forensics and toxicology; pharmaceutical (small molecule)
• フォーマット: neat
• SMILES記法: CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O
• InChI: 1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
• InChI Key: BGRJTUBHPOOWDU-NSHDSACASA-N

詳細

詳細

(S)-(−)-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects. It is also used as a therapeutic drug for the treatment of depression and somatoform disorders.

アプリケーション

(S)-(−)-Sulpiride may be used as an analytical reference standard for the determination of the drug, in biological samples using hydrophilic interaction liquid chromatography−tandem mass spectrometry (HILIC−MS/MS) and reversed-phase high-performance liquid chromatography with fluorescence detection (HPLC-FD).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生物化学的／生理学的作用

D₂ド-パミンレセプタ-アンタゴニストであり、抗精神病薬です。

法的情報

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)