46165

デキサメタゾン

VETRANAL^®, analytical standard

• 別名: (11β,16α)-9-フルオロ-11,17,21-トリヒドロキシ-16-メチルプレグナ-1,4-ジエン-3,20-ジオン, 9α-フルオロ-16α-メチル-11β,17α,21-トリヒドロキシ-1,4-プレグナジエン-3,20-ジオン, 9α-フルオロ-16α-メチルプレドニゾロン, プレドニゾロンF
• 実験式（ヒル表記法）: C₂₂H₂₉FO₅
• CAS番号: 50-02-2
• 分子量: 392.46
• Beilstein: 2066651
• EC Number: 200-003-9
• MDL番号: MFCD00064136
• UNSPSCコード: 41116107
• PubChem Substance ID: 329757092
• NACRES: NA.24

特性

• グレード: analytical standard
• 品質水準: 100
• 製品種目: VETRANAL^®
• シェルフライフ: limited shelf life, expiry date on the label
• テクニック: HPLC: suitable; gas chromatography (GC): suitable
• mp: 262-264 °C (lit.)
• アプリケーション: clinical
• フォーマット: neat
• 保管温度: 2-8°C
• SMILES記法: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
• InChI Key: UREBDLICKHMUKA-CXSFZGCWSA-N
• 遺伝子情報: human ... NR3C1(2908)

詳細

詳細

Dexamethasone is a synthetic glucocorticoid and cortisol analogue. It is used in the suppression of adrenocorticotropic hormone (ACTH) and cortisol production in normal subjects.

アプリケーション

Dexamethasone may be used as a reference standard in the determination of dexamethasone in biological samples using high-performance liquid chromatography (HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生物化学的／生理学的作用

グルココルチコイド・抗炎症剤。T細胞の生存、成長、分化を調節します。一酸化窒素合成酵素の誘導を阻害します。

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Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

法的情報

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Danger
• 危険有害性情報: H360FD
• 注意書き: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危険有害性の分類: Repr. 1B
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves