LIGHTOX14

LightOx^™14

≥98% (HPLC)

• 実験式（ヒル表記法）: C₂₃H₂₅NO₂
• CAS番号: 198696-03-6
• 分子量: 347.45
• UNSPSCコード: 12352101
• NACRES: NA.22

特性

• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 保管温度: 2-8°C
• SMILES記法: N1(CCC(c2c1ccc(c2)C#Cc3ccc(cc3)C(=O)O)(C)C)C(C)C
• InChI: 1S/C23H25NO2/c1-16(2)24-14-13-23(3,4)20-15-18(9-12-21(20)24)6-5-17-7-10-19(11-8-17)22(25)26/h7-12,15-16H,13-14H2,1-4H3,(H,25,26)

詳細

アプリケーション

Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy.

生物化学的／生理学的作用

Strong ligand for retinoic acid receptor proteins

特徴および利点

LightOx14 is a synthetic analogue of all-trans-retinoic acid (ATRA) that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx14 can be utilized to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy.

Product can be used with our line of photoreactors: Including Penn PhD (Z744035) & SynLED 2.0 (Z744080)

その他情報

Chemical Equivalency 1ea=1mg

法的情報

LightOx is a trademark of LightOx Ltd.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable