C4542

シクロベンザプリン 塩酸塩

• 別名: 5-(3-ジメチルアミノプロピリデン)ジベンゾ[a,e]シクロヘプタトリエン 塩酸塩
• 実験式（ヒル表記法）: C₂₀H₂₁N · HCl
• CAS番号: 6202-23-9
• 分子量: 311.85
• EC Number: 228-264-4
• MDL番号: MFCD00079039
• UNSPSCコード: 12352200
• PubChem Substance ID: 24278315
• NACRES: NA.77

特性

• フォーム: powder
• 品質水準: 200
• オーガナイザー: Johnson & Johnson
• SMILES記法: Cl.CN(C)CC\C=C1\c2ccccc2C=Cc3ccccc13
• InChI: 1S/C20H21N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-14H,7,15H2,1-2H3;1H
• InChI Key: VXEAYBOGHINOKW-UHFFFAOYSA-N
• 遺伝子情報: human ... HTR2A(3356) , HTR2B(3357) , HTR2C(3358)

詳細

詳細

Cyclobenzaprine is a tricyclic agent, which has anti-depressant and anti-cholinergic properties. It lowers the tonic somatic motor activity of motor neuron systems. Cyclobenzaprine prevents the uptake of noradrenaline. It is used to treat neck, back and myofascial pain. Cyclobenzaprine functions as a nerve impulse inhibitor.

アプリケーション

Cyclobenzaprine hydrochloride has been used to study its effect on the muscles of dystrophin-deficient mdx5Cv mice.

Cyclobenzaprine hydrochloride has been used to study its effects on the muscles of dystrophin-deficient mdx5Cv mice.

生物化学的／生理学的作用

骨格筋弛緩薬で、脳幹神経の抑制により筋痙縮を低下させます。5-HT₂ セロトニンレセプタ-アンタゴニストです。

Cyclobenzaprine hydrochloride is a type of tricyclic skeletal drug, which is commonly used as a muscle relaxant. It is very effective in treating intractable pain of cervical and lumbar origin caused by skeletal muscle spasm. cyclobenzaprine hydrochloride inhibit tonic α-mononeuronal excitation mediated by descending serotonergic systems by interacting with serotonin receptors at the spinal cord level.

特徴および利点

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

安全性情報

• ピクトグラム: GHS06
• シグナルワード: Danger
• 危険有害性情報: H301,H312 + H332
• 注意書き: P261 - P264 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P312
• 危険有害性の分類: Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation
• 保管分類コード: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves