C5105

抗カルシウムチャネル(α₂/δ-1 サブユニット) ウサギ宿主抗体

affinity isolated antibody, lyophilized powder

• 別名: Anti-CACNA2, Anti-CACNL2A, Anti-CCHL2A, Anti-LINC01112, Anti-lncRNA-N3
• MDL番号: MFCD02686000
• UNSPSCコード: 12352203
• NACRES: NA.43
• 結合体: unconjugated
• application: WB CL
• クローン: polyclonal
• 化学種の反応性: mouse, rat, pig, human
• citations: 16
• テクニック: western blot (chemiluminescent): 1:200 using rat brain membranes

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: lyophilized powder
• 化学種の反応性: mouse, rat, pig, human
• テクニック: western blot (chemiluminescent): 1:200 using rat brain membranes
• UniProtアクセッション番号: P54289
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CACNA2D1(781) ; mouse ... Cacna2d1(12293) ; rat ... Cacna2d1(25399)

詳細

詳細

CACNA2D1 (calcium channel, voltage-dependent, α2/δ subunit 1) is a member of a family of GPI-anchored voltage-gated calcium channels (VGCCs)-associated subunits called α2δ. VGCC are composed of three types of subunits- pore-forming α1 and auxiliary β and α2δ subunits.

免疫原

ウサギカルシウムチャネルα₂/δ−1前駆体のアミノ酸27-41に相当する合成ペプチド。この配列はウサギ, ブタ, ヒトで同一です。ラット, マウスと高い相同性があります(14/15アミノ酸一致)。

アプリケーション

Anti-Calcium Channel (α2/δ-1 Subunit) antibody produced in rabbit has been used in immunoblotting and immunofluorescence.

生物化学的／生理学的作用

CACNA2D1 (calcium channel, voltage-dependent, α2/δsubunit 1) is a type of α2δs, which are involved in the synaptic neurotransmitter release as they are concentrated at the synapses. They have a chaperone-like activity in non-neuronal cells. This protein acts as a target for gabapentin, which is a neuropathic analgesic. Mutations in this gene, in humans result in short QT syndrome (SQTS).

ターゲットの説明

L-type of Voltage-gated Ca²⁺ Channel.

物理的形状

凍結乾燥品 (PBS, pH 7.4, 1%BSA, 0.05%アジ化ナトリウム含有)。

調製ノート

0.05 mLのバイアルは、50 μLの脱イオン水で復元してください。0.2 mLのバイアルは、0.2 mLの脱イオン水で復元してください。復元後の抗体濃度は約0.8 mg/mLです。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable