H9034

Hepatitis C virus core antigen

~1 mg/mL, ≥95% (SDS-PAGE), recombinant, expressed in E. coli

• MDL番号: MFCD02264926
• UNSPSCコード: 12352202
• NACRES: NA.32

特性

• リコンビナント: expressed in E. coli
• 品質水準: 200
• アッセイ: ≥95% (SDS-PAGE)
• 分子量: 22 kDa (plus 114 kDa galactosidse)
• 濃度: ~1 mg/mL
• UniProtアクセッション番号: G9G988; L7S4V3
• 輸送温度: dry ice
• 保管温度: −20°C
• 遺伝子情報: hepatitis C virus ... HCVgp1(951475) ; human ... HBVgp4(944568)

詳細

詳細

Hepatitis C virus core antigen (HCV-cAg) is a well-preserved antigenic protein of the internal capsid.

Hepatitis C virus glycoprotein 1 (HCVgp1), also referred to as polyprotein, is crucial for the induction of double-membrane vesicles, sites of HCV RNA amplification. The amino terminal of polyprotein contains the structural proteins core, envelope protein 1 (E1) and E2. The proteolytic cleavage of polyprotein results in the formation of 10 mature viral proteins which are needed for viral replication and assembly.

amino acids 2-192 of HCV polyprotein

特異性

Reacts strongly with human HCV positive serum.

アプリケーション

Hepatitis core antigen (HCA) has been used as an analyte in enzyme-linked immunosorbent assay (ELISA) to study the mechanism of bovine serum albumin (BSA) blocking in common ELISA protocols.

生物化学的／生理学的作用

Hepatitis C virus core antigen (HCV-cAg) may be a less expensive way to diagnose active hepatitis C virus (HCV) infection in the hemodialysis (HD) population.

Positive control for HCV antibodies.

その他情報

HCV core antigen [2-192]-Galactosidase-tagged at the N-terminus.

物理的形状

Solution in 8 M Urea, 20 mM Tris-HCl, pH 8.0, 10 mM 2-mercaptoethanol.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable