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Artur Schmidtchen et al.
The Journal of biological chemistry, 284(26), 17584-17594 (2009-04-29)
A novel approach for boosting antimicrobial peptides through end tagging with hydrophobic oligopeptide stretches is demonstrated. Focusing on two peptides derived from kininogen, GKHKNKGKKNGKHNGWK (GKH17) and HKHGHGHGKHKNKGKKN (HKH17), tagging resulted in enhanced killing of Gram-positive Staphylococcus aureus, Gram-negative Escherichia coli
Joyce J C Kroot et al.
American journal of hematology, 87(10), 977-983 (2012-08-14)
Measurements of the iron regulatory hormone hepcidin by various methodologies and laboratories are not harmonized. As a result different numeric results are obtained for the same clinical sample. We investigated whether better agreement between plasma hepcidin methods can be achieved
Magdalena Banas et al.
PloS one, 8(3), e58709-e58709 (2013-03-26)
Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share similar tertiary structure with antibacterial cathelicidins. Recombinant chemerin has antimicrobial activity. Here we show that endogenous chemerin is abundant in human epidermis, and that inhibition of bacteria
Yi Tian et al.
Nature communications, 12(1), 481-481 (2021-01-22)
T helper type 17 (Th17) cells have important functions in the pathogenesis of inflammatory and autoimmune diseases. Retinoid-related orphan receptor-γt (RORγt) is necessary for Th17 cell differentiation and functions. However, the transcriptional regulation of RORγt expression, especially at the enhancer
Linn S Strandberg et al.
PloS one, 8(9), e72668-e72668 (2013-09-17)
Congenital heart block (CHB) is a transplacentally acquired autoimmune disease associated with anti-Ro/SSA and anti-La/SSB maternal autoantibodies and is characterized primarily by atrioventricular (AV) block of the fetal heart. This study aims to investigate whether the T-type calcium channel subunit
資料
カスタムでのペプチド合成を選択する際には、その設計過程でいくつかの重要な要素を検討する必要があります。検討事項には、配列長、溶解度、配列安定性などがあります。
Consider sequence length, solubility, and stability when designing peptides for custom synthesis.
関連コンテンツ
Peptide synthesis up to 200 amino acids with HPLC purification, offering various purity levels, scales, and modifications.
最先端の固相担体を使って200アミノ酸残基までのペプチドを合成し、HPLCによりペプチドを精製します。純度や合成スケールの変更など、さまざまな修飾にも対応します。
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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