PRS4059

Anti-PDL-1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: 抗IPS-1抗体
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: predicted mol wt 32 kDa
• 化学種の反応性: human, rat, mouse
• テクニック: flow cytometry: suitable; immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProtアクセッション番号: Q9NZQ7
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... CD274(29126)

詳細

詳細

PDL-1 (programmed cell death 1 ligand 1) is a cell surface protein, that is also known as B7-H1 (B7 homolog 1), coded by CD274 (cluster of differentiation 274) gene. It is located on chromosome 9p24.1. It is present on placental cells, vascular endothelial cells, liver cells, epithelial cells, mesenchymal stem cells, B cells, T cells, dendritic cells and macrophages. It is also expressed in various tumor types like melanoma, glioblastoma, cancers in the lung, kidney, head, neck, stomach, colon, pancreas, breast, cervix and ovary.

免疫原

17 amino acid peptide from near the center of human PDL-1.

生物化学的／生理学的作用

PDL-1 (programmed cell death 1 ligand 1) helps to clear sudden HPV (human papilloma virus) infections. It prevents the multiplication and adherence of T-cell and production of cytokine. It also controls the activities of T-cells in peripheral tissues.

関連事項

The action of this antibody can be blocked using blocking peptide SBP4059.

物理的形状

PBS溶液(0.02%アジ化ナトリウム含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable