RAB1122

Mouse EPO ELISA Kit

for cell culture supernatants, plasma, and serum samples

• UNSPSCコード: 41116158
• NACRES: NA.32

特性

• 化学種の反応性: mouse
• 包装: kit of 96 wells (12 strips x 8 wells)
• テクニック: ELISA: suitable
• 入力: sample type cell culture supernatant(s); sample type plasma; sample type serum sample(s)
• assay range: inter-assay cv: <12%; intra-assay cv: <10%; sensitivity: 1.5 pg/ml
• 検出方法: colorimetric
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: mouse ... Epo(13856)

詳細

詳細

This ELISA antibody pair detects Mouse Erythropoietin (EPO)

アプリケーション

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生物化学的／生理学的作用

Erythropoietin (EPO) is a glycoprotein hormone which is essential for the proliferation of erythropoietic progenitors to produce red blood cells (RBCs). Peritubular fibroblast in kidney cortex is the primary site for EPO production in adults, though spleen, bone marrow and liver contribute to the production. In fetus, liver is the primary site for EPO production. Additionally, EPO functions in some cytoprotective activities like, antiapoptotic, antioxidant, and anti-inflammatory responses. Hypoxia inducible factors upregulate EPO expression. EPO expression increases with decreased hemoglobin concentration in few cases of anemia. Decreased production of EPO is the cause of anemia in chronic kidney diseases. Circulating endogenous antibodies to EPO (anti-EPO) is the cause of anemia in multiple diseases like human immunodeficiency virus (HIV) infection, hepatitis C virus infection, systemic lupus erythematosus. Gain-of-function polymorphism in EPO causes familial erythrocytosis.

その他情報

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

安全性情報

• ピクトグラム: GHS05
• シグナルワード: Warning
• 危険有害性情報: H290
• 注意書き: P234 - P390
• 危険有害性の分類: Met. Corr. 1
• 保管分類コード: 8A - Combustible corrosive hazardous materials
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable