SAB4200175

Anti-Atg101 antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 別名: Anti-Atg13-interacting protein, Anti-C12orf44, Anti-autophagy-related protein 101, Anti-chromosome 12 open reading frame 44
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: WB
• クローン: polyclonal
• 化学種の反応性: human
• citations: 12
• テクニック: western blot: 0.25-0.5 μg/mL using whole extracts of HEK-293T cells over expressing human Atg101

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: ~30 kDa
• 化学種の反応性: human
• 濃度: ~1.0 mg/mL
• テクニック: western blot: 0.25-0.5 μg/mL using whole extracts of HEK-293T cells over expressing human Atg101
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... C12orf44(60673)

詳細

詳細

Autophagy101 (Atg101) is located on the human chromosome at 12q13.13.

アプリケーション

Anti-Atg101 antibody has been used in

• immunoblotting
• immunofluorescence
• immunopurification

生物化学的／生理学的作用

Autophagy101 (Atg101) is a mammalian Autophagy13 (Atg13) binding protein essential for autophagy. Atg13 forms a stable complex with ULK1 (Serine/threonine-protein kinase ULK1) and FIP200 (FAK family kinase-interacting protein of 200 kDa). Atg101 associates with the ULK1-Atg13- FIP200 complex through direct interaction with Atg13. Mammalian target of rapamycin (mTOR) interacts with the ULK1-Atg13-FIP200 complex in a nutrient dependent manner, suggesting that mTOR regulates autophagy through this complex.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable