SAB4200717

Anti-Troponin T antibody, Mouse monoclonal

clone JLT-12, purified from hybridoma cell culture

• 別名: Anti-TNNT1, Anti-TNNT2
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 200
• 抗体製品の状態: purified from hybridoma cell culture
• 抗体製品タイプ: primary antibodies
• クローン: JLT-12, monoclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~38 kDa
• 化学種の反応性: rat, human, mouse, bovine, rabbit, goat
• 濃度: ~1.0 mg/mL
• テクニック: immunoblotting: 0.5-1 μg/mL using rat skeletal muscle extract; immunofluorescence: suitable; immunohistochemistry: 5-10 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human skeletal muscle sections
• アイソタイプ: IgG1
• UniProtアクセッション番号: P13805
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... TNNT1(7138)

詳細

詳細

Anti-Troponin T antibody, Mouse monoclonal, (mouse IgG1 isotype) is derived from the JLT-12 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with purified Troponin T from rabbit skeletal muscle. Troponin T (TNNT) is the tropomyosin binding subunit of the troponin complex. Three genes have evolved to encode the cardiac (TNNT2), slow (TNNT1) and fast (TNNT3) skeletal muscle Troponin T proteins, which are specifically expressed in cardial, slow and fast skeletal muscles, respectively.

免疫原

purified Troponin T from rabbit skeletal muscle

アプリケーション

• Anti-Troponin T antibody, Mouse monoclonal has been used in:
• immunoblotting
• immunofluorescence
• immunohistochemistry

生物化学的／生理学的作用

Troponin T (TNNT) participates in calcium regulation of actin thin filament function and is required for the contraction of striated muscles. Levels of cardiac Troponin T serve as a sensitive biomarker of myocardial injury. Troponin T has also been suggested as a potential marker in diagnosis of skeletal myopathies including amyotrophic lateral sclerosis (ALS).

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable