SAB4300400

Anti-PRKD1 (Ab-910) antibody produced in rabbit

affinity isolated antibody

• 別名: Anti-PKC-MU antibody produced in rabbit, Anti-PKCM antibody produced in rabbit, Anti-PKD antibody produced in rabbit, Anti-PRKCM antibody produced in rabbit, Anti-protein kinase D1 antibody produced in rabbit
• MDL番号: MFCD03455823
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: ~115 kDa
• 化学種の反応性: human, mouse
• 濃度: 1 mg/mL
• テクニック: western blot: 1:500-1:1000
• アイソタイプ: IgG
• 免疫原配列: (R-V-S-I-L)
• NCBIアクセッション番号: NP_002733.2
• UniProtアクセッション番号: Q15139
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... PRKD1(5587)

詳細

詳細

PRKD1 gene encodes PKD1 (protein kinase D1), that belongs to the protein kinase D family. It is a serine/threonine kinase, which is expressed in cells of the normal mammary gland. The PRKD1 gene promoter has a great CpG island covering 1.2kb, including the transcription start site and the entire exon 1.

免疫原

Peptide sequence around aa. 908-912 (R-V-S-I-L), according to the protein PRKD1.

生物化学的／生理学的作用

PRKD1 (Protein kinase D 1) is a negative modulator of cell migration . It plays an important role in cell adhesion, cell migration, vesicle transport, cell survival , signal transduction, membrane trafficking and immune function. It preserves the epithelial phenotype by inhibiting epithelial-to-mesenchymal transition.

特徴および利点

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ターゲットの説明

Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable