SAB4700391

Monoclonal Anti-CD11c-APC antibody produced in mouse

clone BU15, purified immunoglobulin, buffered aqueous solution

• 別名: Anti-ITGAX
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: Allophycocyanin conjugate
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: BU15, monoclonal
• 形状: buffered aqueous solution
• 化学種の反応性: human, monkey, canine
• テクニック: flow cytometry: suitable
• アイソタイプ: IgG1
• NCBIアクセッション番号: NM_000887.3
• UniProtアクセッション番号: P20702
• 輸送温度: wet ice
• 保管温度: 2-8°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ITGAX(3687)

詳細

詳細

Cluster of differentiation 11c (CD11c), also known as integrin subunit α X (ITGAX), is an antigen receptor, encoded by the gene mapped to human chromosome 16p11.2. The encode protein belongs to the adhesion molecule integrin family and is mainly expressed in natural killer cells, macrophages and even some activated B and T cells.

The antibody BU15 reacts with CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.

免疫原

Dendritic cells of synovial fluid

アプリケーション

The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (1 mL) is sufficient for 100 tests.

生物化学的／生理学的作用

Cluster of differentiation 11c (CD11c) delivers co-stimulatory signals to activated lymphocytes. Elevated expression of the gene decreased the risk of death and relapse in gastric cancer (GC) patients. The protein can be considered as an alternative prognosis marker for GC. Overexpression of CD11c in CD8⁺ cells might lead to the development of Behcet′s disease (BD).

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

物理的形状

PBS（15 mM アジ化ナトリウム、安定化剤として0.2％ハイグレード プロテアーゼフリーBSA含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable