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由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous glycerol solution
分子量
antigen predicted mol wt 420 kDa
化学種の反応性
mouse, rat, human
濃度
1 mg/mL
テクニック
immunohistochemistry: suitable
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... BSN(8927)
詳細
Bassoon presynaptic cytomatrix protein (BSN) is a 420kDa protein which is expressed in the neuronal synapses. The gene encoding it is located on human chromosome 3p21. The gene ID of the protein is 8927.
特異性
Detects ~420 kDa, corresponding to the molecular mass of Bassoon. Multiple isoforms can be detected.
免疫原
NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein
生物化学的/生理学的作用
Bassoon presynaptic cytomatrix protein (BSN) acts as a scaffold protein and mediates release of neurotransmitters. It is also a part of trafficking and helps in delivery of proteins across the synapse.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
PBS, pH 7..4, 50% glycerol, 0.09% sodium azide
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
SAB5200101-100UG:
最新バージョンのいずれかを選択してください:
Genomics, 57(3), 389-397 (1999-05-18)
Bassoon is a novel 420-kDa protein recently identified as a component of the cytoskeleton at presynaptic neurotransmitter release sites. Analysis of the rat and mouse sequences revealed a polyglutamine stretch in the C-terminal part of the protein. Since it is
Neuron, 68(4), 710-723 (2010-11-26)
Sustained rate-coded signals encode many types of sensory modalities. Some sensory synapses possess specialized ribbon structures, which tether vesicles, to enable high-frequency signaling. However, central synapses lack these structures, yet some can maintain signaling over a wide bandwidth. To analyze
Nature, 447(7145), 661-678 (2007-06-08)
There is increasing evidence that genome-wide association (GWA) studies represent a powerful approach to the identification of genes involved in common human diseases. We describe a joint GWA study (using the Affymetrix GeneChip 500K Mapping Array Set) undertaken in the
Cell, 179(2), 498-513 (2019-10-05)
Neuromodulators bind to pre- and postsynaptic G protein-coupled receptors (GPCRs), are able to quickly change intracellular cyclic AMP (cAMP) and Ca2+ levels, and are thought to play important roles in neuropsychiatric and neurodegenerative diseases. Here, we discovered in human neurons
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