SML0252

Anisodamine

≥98% (HPLC)

• 別名: α-(Hydroxymethyl)-benzeneacetic acid 6-hydroxy-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, 6β-Hydroxyhyoscyamine, 6-Hydroxyhyoscyamine
• 実験式（ヒル表記法）: C₁₇H₂₃NO₄
• CAS番号: 55869-99-3
• 分子量: 305.37
• UNSPSCコード: 12352116
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: H₂O: ≥5 mg/mL
• 保管温度: room temp
• SMILES記法: CN1[C@H]2C(O)C[C@@H]1C[C@H](OC(C(CO)C3=CC=CC=C3)=O)C2
• InChI: 1S/C17H23NO4/c1-18-12-7-13(9-15(18)16(20)8-12)22-17(21)14(10-19)11-5-3-2-4-6-11/h2-6,12-16,19-20H,7-10H2,1H3/t12-,13-,14+,15+,16-/m0/s1
• InChI Key: WTQYWNWRJNXDEG-RBZJEDDUSA-N

詳細

詳細

Racemic mixture of diastereomers.

生物化学的／生理学的作用

Anisodamine is a muscarinic receptor antagonist. Anisodamine is a naturally occurring atropine derivative isolated from Scopolia Tangutica Maxim plant indigenous to Tibet.

Anisodamine is a non‐specific cholinergic antagonist. It is considered less efficient and less toxic than atropine. Anisodamine interferes with liposome structure and affects cell membrane. It might act as an anti‐oxidant, in protecting against the damage caused by free radicals. Anisodamine is known to reduce cardiac conduction and also prevents arrhythmia. It can block thromboxane synthesis and might possess anti‐thrombotic function. Anisodamine has been useful in a number therapies including septic shock, circulatory disorders, organophosphorus poisoning, opiate addiction, snake bite and radiation damage. Disorders, such as migraine, gastric ulcers, rheumatoid arthritis, gastrointestinal colic, eclampsia, respiratory diseases, acute glomerular nephritis and obstructive jaundice can be treated with the help of anisodamine.

特徴および利点

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302,H319
• 注意書き: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Irrit. 2
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable