SML3508

Intepirdine

≥98% (HPLC)

• 別名: 3-(Phenylsulfonyl)-8-(1-piperazinyl)quinoline, 3-Phenylsulfonyl-8-(piperazin-1-yl)quinoline, GSK 742457, RVT 101, SB-742457
• 実験式（ヒル表記法）: C₁₉H₁₉N₃O₂S
• CAS番号: 607742-69-8
• 分子量: 353.44
• MDL番号: MFCD12828872
• UNSPSCコード: 51111800
• UNSPSCコード: 12352200
• NACRES: NA.21

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• フォーム: powder
• 色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear
• 保管温度: 2-8°C
• SMILES記法: O=S(C1=CC=CC=C1)(C2=CC3=C(N=C2)C(N4CCNCC4)=CC=C3)=O

詳細

生物化学的／生理学的作用

Intepirdine (SB-742457) is a brain blood barrier penetrant, orally available, potent and selective serotonin receptor 6 (5-HT6) receptor antagonist that potentiate cognitive and the behavioral abnormalities of AD in laboratory set up. Intepirdine has failed to demonstrate statistically significant impact on cognition or dementia in phase III trials. Intepirdine promotes satiety.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable