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Merck

T4071

SAFC

L-トレオニン

医薬品製造

別名:

(2S,3R)-2-アミノ-3-ヒドロキシ酪酸

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About This Item

化学式:
CH3CH(OH)CH(NH2)CO2H
CAS番号:
分子量:
119.12
Beilstein:
1721646
EC Number:
MDL番号:
UNSPSCコード:
12352209
NACRES:
NA.26

由来生物

non-animal source

品質水準

アッセイ

≥98.5%

フォーム

crystalline powder

テクニック

cell culture | mammalian: suitable

不純物

endotoxin, heavy metals, trace metals, residual solvents, tested

mp

256 °C (dec.) (lit.)

溶解性

H2O: 50 mg/mL

適合性

suitable for manufacturing use

その他の活性

cytotoxicity, tested

SMILES記法

C[C@@H](O)[C@H](N)C(O)=O

InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1

InChI Key

AYFVYJQAPQTCCC-GBXIJSLDSA-N

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詳細

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

アプリケーション

L-Threonine is a β-hydroxy-α-amino acid. It is an essential amino acid and can be used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

法的情報

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類コード

11 - Combustible Solids

WGK

WGK 1

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, type N95 (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

T4071-BULK:
T4071-100G:
T4071-10KG:
T4071-25KG:
2560070:
T4071-1KG:
T4071-VAR:


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L-トレオニン Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1242

L-トレオニン

L-Serine EMPROVE® EXPERT Ph Eur,USP

SAFC

1.07647

L-Serine

L-Threonine for biochemistry

Millipore

1.08411

L-Threonine

L-プロリン

SAFC

P8865

L-プロリン

Tamara Seredenina et al.
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Voltage-gated proton channels are increasingly implicated in cellular proton homeostasis. Proton currents were originally identified in snail neurons less than 40 years ago, and subsequently shown to play an important auxiliary role in the functioning of reactive oxygen species (ROS)-generating
Chang-Ching Liu et al.
Molecular and cellular biology, 34(1), 57-70 (2013-10-30)
In budding yeast (Saccharomyces cerevisiae), the cell cycle-dependent telomere elongation by telomerase is controlled by the cyclin-dependent kinase 1 (Cdk1). The telomere length homeostasis is balanced between telomerase-unextendable and telomerase-extendable states that both require Cdc13. The recruitment of telomerase complex
Mario Ost et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 29(4), 1314-1328 (2014-12-11)
Recent studies on mouse and human skeletal muscle (SM) demonstrated the important link between mitochondrial function and the cellular metabolic adaptation. To identify key compensatory molecular mechanisms in response to chronic mitochondrial distress, we analyzed mice with ectopic SM respiratory
Anne-Sophie Van Rompuy et al.
Journal of neuropathology and experimental neurology, 73(2), 159-174 (2014-01-16)
Mutations in the parkin gene are the most common cause of early-onset autosomal recessive Parkinson disease (PD). The pathogenic mechanisms of how parkin mutations lead to the development of PD are not fully understood. Studies of cell cultures and of
Sarah Schmidt et al.
Journal of leukocyte biology, 98(1), 5-14 (2015-02-04)
The deoxynucleoside triphosphate triphosphohydrolase and 3' → 5' exonuclease SAMHD1 restricts HIV-1 infection in noncycling hematopoietic cells in vitro, and SAMHD1 mutations are associated with AGS. Little is known about the in vivo expression and functional regulation of this cellular

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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