U6758

UCL 2077

≥98% (HPLC), solid

• 別名: (3-Triphenylmethylaminomethyl)pyridine
• 実験式（ヒル表記法）: C₂₅H₂₂N₂
• CAS番号: 918311-87-2
• 分子量: 350.46
• MDL番号: MFCD00585879
• UNSPSCコード: 12352200
• PubChem Substance ID: 329827644
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥98% (HPLC)
• 形状: solid
• 色: white
• 溶解性: DMSO: soluble >20 mg/mL; H₂O: insoluble
• SMILES記法: C(NC(c1ccccc1)(c2ccccc2)c3ccccc3)c4cccnc4
• InChI: 1S/C25H22N2/c1-4-12-22(13-5-1)25(23-14-6-2-7-15-23,24-16-8-3-9-17-24)27-20-21-11-10-18-26-19-21/h1-19,27H,20H2
• InChI Key: PQFNWDHABGBCHB-UHFFFAOYSA-N

詳細

アプリケーション

UCL 2077 has been used for slow afterhyperpolarization (sAHP) studies in thalamic paraventricular nucleus (PVT) neurons. UCL 2077 has also been used for studying its effects on the increase in excitability of hippocampal pyramidal cells.

生物化学的／生理学的作用

UCL 2077 is a slow afterhyperpolarization (sAHP) channel blocker.

調製ノート

UCL 2077 is soluble in DMSO at a concentration >20 mg/ml and is insoluble in water.

安全性情報

• ピクトグラム: GHS07
• シグナルワード: Warning
• 危険有害性情報: H302,H315,H319,H335
• 注意書き: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• ターゲットの組織: Respiratory system
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): dust mask type N95 (US), Eyeshields, Faceshields, Gloves