WH0003558M3

Monoclonal Anti-IL2 antibody produced in mouse

clone 3C8, purified immunoglobulin, buffered aqueous solution

• 別名: Anti-IL2, Anti-TCGF, Anti-interleukin 2, Anti-lymphokine
• MDL番号: MFCD00675261
• UNSPSCコード: 12352203
• NACRES: NA.41
• 結合体: unconjugated
• application: ELISA (i)
• クローン: 3C8, monoclonal
• 化学種の反応性: human
• citations: 4
• テクニック: indirect ELISA: suitable

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: 3C8, monoclonal
• フォーム: buffered aqueous solution
• 化学種の反応性: human
• テクニック: indirect ELISA: suitable
• アイソタイプ: IgG2aκ
• GenBankアクセッション番号: N/A
• UniProtアクセッション番号: P60568
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... IL2(3558)

詳細

詳細

Interleukin 2 (IL2) is synthesised by immunoregulatory T helper cells. IL2 consists of three subunits, in which the beta subunit is critical for receptor mediated signalling. IL2 gene is located on human chromosome 4q27.

免疫原

IL2 (NP_000577, 21 a.a. ~ 153 a.a) recombinant protein.

Sequence
MAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSQSIISTLT

生物化学的／生理学的作用

Interleukin 2 (IL2) promotes the development of suppressor T regulatory cells. IL2 plays a crucial role in antitumor immunity. IL2 destabilises adherens junctions, and cytoskeletal reorganization, causing increased endothelial cell permeability.

物理的形状

Solution in phosphate buffered saline, pH 7.4

法的情報

GenBank is a registered trademark of United States Department of Health and Human Services

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)