568533-U
Discovery® HS C18 (5 µm) HPLC Columns
L × I.D. 25 cm × 10 mm, HPLC Column
別名:
Discovery RP18 HPLC Column
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About This Item
UNSPSCコード:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × 内径:
25 cm × 10 mm
表面積:
300 m2/g
粒径:
5 μm
マトリックス活性基:
C18 (octadecyl) phase
ポアサイズ:
120 Å
Matrix:
silica gel, high purity, spherical particle platform
fully porous particle
fully porous particle
おすすめの製品
製品名
Discovery® HS C18 HPLCカラム, 5 μm particle size, L × I.D. 25 cm × 10 mm
物質
stainless steel column
品質水準
認証
suitable for USP L1
製品種目
Discovery®
特徴
endcapped
メーカー／製品名
Discovery®
包装
1 ea of
標識化の程度
20% Carbon loading
パラメーター
≤70 °C temp. range
400 bar pressure (5801 psi)
テクニック
HPLC: suitable
L × 内径
25 cm × 10 mm
表面積
300 m2/g
表面被覆率
3.2 μmol/m2
不純物
<10 ppm metals
Matrix
silica gel, high purity, spherical particle platform
fully porous particle
マトリックス活性基
C18 (octadecyl) phase
粒径
5 μm
ポアサイズ
120 Å
動作pH範囲
2-8
アプリケーション
food and beverages
分離法
reversed phase
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詳細
Discovery® HS C18 HPLC column is specifically developed for pharmaceutical analyses and purification.
アプリケーション
- Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping: This research utilizes the Discovery® HS C18 HPLC column for its superior selectivity and sensitivity in pharmacogenetic studies, providing vital data for personalized medicine approaches in drug metabolism (Abouir et al., 2024).
- A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies: This study highlights the effectiveness of the Discovery® HS C18 column in the rapid and accurate analysis of molnupiravir, emphasizing its role in supporting fast-paced pharmaceutical research and development (Reçber et al., 2022).
- Sensitive Analysis of Idarubicin in Human Urine and Plasma by Liquid Chromatography with Fluorescence Detection: This application underlines the Discovery® HS C18 column′s high sensitivity and robustness in clinical diagnostics, crucial for monitoring therapeutic drugs and their metabolites in complex biological matrices (Maliszewska et al., 2020).
特徴および利点
- 安定で、低ブリ-ドのLC-MS分離
- 分析から分取まで適応可能
- 安定性が高く、操作間、ロット間の再現性を保証
- 疎水性が高く、難しい分析対象物の高い分離能
法的情報
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
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Jolanta Flieger et al.
Journal of separation science, 34(7), 733-739 (2011-03-02)
Highly hydrophilic compounds belonging to biogenic amines were analysed in the reversed-phase system, modified with the addition of ionic liquids: 1-ethyl-3-methyl-imidazolium hexafluorophosphate (EMIM PF(6)) and chaotropic salt NaPF(6) on Discovery HS C18 column at acidic conditions. The effect of the
Swati Jaiswal et al.
Journal of chromatographic science, 55(6), 617-624 (2017-03-24)
Tuberculosis (TB) with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome represents the most common infectious diseases worldwide. Anti-TB drugs are used concurrently with antiretroviral drug for treatment of TB-HIV co-morbidities. Due to lower risk of interaction with protease inhibitors, rifabutin is
Bhavin N Patel et al.
Biomedical chromatography : BMC, 22(11), 1213-1224 (2008-07-25)
A simple, precise and accurate assay for the determination of 6-methoxy-2-naphthylacetic acid (6-MNA), an active metabolite of nabumetone in human plasma, was developed and validated using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The analyte (6-MNA) and propranolol (internal standard, IS) were
Abad Khan et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(28), 2782-2788 (2010-09-11)
A rapid, inexpensive, sensitive and specific HPLC-ECD method for the determination of lipoic acid in human plasma was developed and validated over the linearity range of 0.001-10μg/ml using naproxen sodium as an internal standard (IS). Extraction of lipoic acid and
Fazli Khuda et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 944, 114-122 (2013-12-10)
A simple, specific, precise and rapid RP-HPLC-UV method was developed for simultaneous determination of lumefantrine and its metabolite desbutyl lumefantrine in human plasma. Experimental parameters were optimized and the method was validated according to standard guidelines. The method showed adequate
関連コンテンツ
HPLC DiscoveryBIO HS C18 products. Available in 3µm, 5µm and 10µm particle sizes.
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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