おすすめの製品
グレード
pharmaceutical primary standard
APIファミリー
escitalopram, escitalopram
メーカー/製品名
USP
アプリケーション
pharmaceutical (small molecule)
フォーマット
neat
保管温度
2-8°C
SMILES記法
OC(=O)C(O)=O.CN(C)CCC[C@]1(OCc2cc(ccc12)C#N)c3ccc(F)cc3
InChI
1S/C20H21FN2O.C2H2O4/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20;3-1(4)2(5)6/h4-9,12H,3,10-11,14H2,1-2H3;(H,3,4)(H,5,6)/t20-;/m0./s1
InChI Key
KTGRHKOEFSJQNS-BDQAORGHSA-N
遺伝子情報
human ... SLC6A4(6532)
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詳細
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the authority of the issuing pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Escitalopram oxalate, the S-enantiomer of racemic citalopram, belongs to the class of compounds known as antidepressants, that works as a selective serotonin-reuptake inhibitor (SSRI).
Escitalopram oxalate, the S-enantiomer of racemic citalopram, belongs to the class of compounds known as antidepressants, that works as a selective serotonin-reuptake inhibitor (SSRI).
アプリケーション
Escitalopram oxalate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
- Escitalopram Oral Solution
- Escitalopram Oxalate
- Escitalopram Tablets
生物化学的/生理学的作用
エスシタロプラムは、選択的セロトニン再取り込み阻害薬(SSRI)であり、シタロプラムのS-エナンチオマーでありオイトマーです。
アナリシスノート
These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
その他情報
Sales restrictions may apply.
シグナルワード
Warning
危険有害性情報
危険有害性の分類
Acute Tox. 4 Dermal - Acute Tox. 4 Oral
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
毒物及び劇物取締法
劇物
Jan Code
1249406-200MG:4548173918198
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Spectrophotometric and reversed-phase high-performance liquid chromatographic methods for simultaneous determination of escitalopram oxalate and clonazepam in combined tablet dosage form
Journal of AOAC (Association of Official Analytical Chemists) International, 91(1), 33-38 (2008)
Behavioural brain research, 273, 155-165 (2014-07-22)
Serotonergic (5-HT) drugs are widely used in the clinical management of mood and anxiety disorders. However, it is reported that acute 5-HT treatment elicits anxiogenic-like behavior. Interestingly, the periaqueductal gray (PAG), a midbrain structure which regulates anxiety behavior - has
Application Of Stability Indicating Hptlc Method For Quantitative Determination Of Escitalopram Oxalate In Pharmaceutical Dosage Form.
Eurasian Journal of Analytical Chemistry, 2(2) (2007)
Simultaneous HPTLC determination of escitalopram oxalate and clonazepam in combined tablets.
Chromatographia, 67(5-6), 487-490 (2008)
Journal of neurotrauma, 31(15), 1334-1342 (2014-04-20)
Incomplete spinal cord injury (iSCI) often results in significant motor impairments that lead to decreased functional mobility. Loss of descending serotonergic (5HT) input to spinal circuits is thought to contribute to motor impairments, with enhanced motor function demonstrated through augmentation
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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