1430735

Methylnaltrexone bromide

United States Pharmacopeia (USP) Reference Standard

• 別名: 17-(Cyclopropylmethyl)-4,5α-epoxy-3,14-dihydroxy-17-methyl-6-oxomorphinanium bromide, MNTX, Methylnaltrexonium, Mrz-2663, N-Methylnaltrexone, Naltrexone MB, Quaternary ammonium naltrexone
• 実験式（ヒル表記法）: C₂₁H₂₆NO₄ · Br
• CAS番号: 73232-52-7
• 分子量: 436.34
• MDL番号: MFCD06407831
• UNSPSCコード: 41116107
• PubChem Substance ID: 329750446
• NACRES: NA.24

特性

• グレード: pharmaceutical primary standard
• APIファミリー: methylnaltrexone
• メーカー／製品名: USP
• アプリケーション: pharmaceutical
• フォーマット: neat
• SMILES記法: [Br-].C[N@+]1(CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@]2(O)CCC4=O)c35)CC6CC6
• InChI: 1S/C21H25NO4.BrH/c1-22(11-12-2-3-12)9-8-20-17-13-4-5-14(23)18(17)26-19(20)15(24)6-7-21(20,25)16(22)10-13;/h4-5,12,16,19,25H,2-3,6-11H2,1H3;1H/t16-,19+,20+,21-,22?;/m1./s1
• InChI Key: IFGIYSGOEZJNBE-KNLJMPJLSA-N
• 遺伝子情報: human ... OPRM1(4988)

詳細

詳細

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

アプリケーション

Methylnaltrexone bromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

生物化学的／生理学的作用

Methylnaltrexone bromide is a narcotic antagonist.

Methylnaltrexone bromide is a narcotic antagonist. It is a peripheral mu-opiod receptor antagonist that cannot cross the blood-brain barrier. It reverses many opioid side-effects without interfering with pain relief.

アナリシスノート

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

その他情報

Sales restrictions may apply.

安全性情報

• ピクトグラム: GHS08
• シグナルワード: Warning
• 危険有害性情報: H371
• 注意書き: P260 - P264 - P270 - P308 + P311 - P405 - P501
• 危険有害性の分類: STOT SE 2 Oral
• ターゲットの組織: Gastrointestinal tract
• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable