10907
Chloroacetaldehyde solution
produced by Wacker Chemie AG, Burghausen, Germany, ≥45.0% in H2O (density determination)
동의어(들):
CLACH
로그인조직 및 계약 가격 보기
모든 사진(1)
About This Item
Linear Formula:
ClCH2CHO
CAS Number:
Molecular Weight:
78.50
Beilstein:
1071226
EC Number:
MDL number:
UNSPSC 코드:
12352100
PubChem Substance ID:
NACRES:
NA.22
추천 제품
Grade
produced by Wacker Chemie AG, Burghausen, Germany
Quality Level
형태
solid
농도
≥45.0% in H2O (density determination)
bp
80-100 °C (lit.)
작용기
aldehyde
chloro
SMILES string
[H]C(=O)CCl
InChI
1S/C2H3ClO/c3-1-2-4/h2H,1H2
InChI key
QSKPIOLLBIHNAC-UHFFFAOYSA-N
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
Chloroacetaldehyde is a reagent used for converting adenine and its nucleoseides into fluorescent etheno derivatives which can be analysed by HPLC. It was used for derivatization in fluorometric determination of arprinocid and analogous compounds in human plasma .
생화학적/생리학적 작용
Chloroacetaldehyde, a metabolite of ifosamide, influences oxidative phosphorylation in mitochondria. It causes breaking of DNA strands and strongly inhibits DNA synthesis.
기타 정보
prices for bulk quantities on request
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Carc. 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point (°F)
143.6 °F - closed cup
Flash Point (°C)
62 °C - closed cup
개인 보호 장비
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Fluorogenic reaction between adenine derivatives and chloroacetaldehyde and its application to the determination of 9-(2-chloro-6-fluorobenzyl) adenine in human plasma.
Matuszewski BK and Bayne WF.
Analytica Chimica Acta, 227, 189-202 (1989)
Svenja K Brüggemann et al.
Cancer chemotherapy and pharmacology, 57(3), 349-356 (2005-09-01)
The ifosfamide metabolite chloroacetaldehyde had been made responsible for side effects only. We found in previous studies a strong cytotoxicity on human MX-1 tumor cells and xenografts in nude mice. Chloroacetaldehyde is supposed to act via alkylation or by inhibition
Preparation, titration, and storage of chloroacetaldehyde for fluorometric determination of adenine and its derivatives.
McCann WP, et al.
Analytical Chemistry, 55(8), 1454-1455 (1983)
Min Young Kim et al.
Chemical research in toxicology, 20(8), 1075-1083 (2007-07-31)
2-Chloroacetaldehyde (CAA), a metabolite of the carcinogen vinyl chloride, reacts with DNA to form cyclic etheno ()-lesions. AlkB, an iron-/alpha-ketoglutarate-dependent dioxygenase, repairs 1, N (6)-ethenodeoxyadenosine (A) and 3, N (4)-ethenodeoxycytidine (C) in site-specifically modified single-stranded viral genomes in vivo and
Leila Choucha-Snouber et al.
Biotechnology and bioengineering, 110(2), 597-608 (2012-08-14)
In this article, we present a liver-kidney co-culture model in a micro fluidic biochip. The liver was modeled using HepG2/C3a and HepaRG cell lines and the kidney using MDCK cell lines. To demonstrate the synergic interaction between both organs, we
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.