176192

Borane tetrahydrofuran complex solution

1.0 M in THF

• 동의어(들): Borane-THF (1:1), Boron hydride (BH₃)-THF (1:1), Tetrahydrofuran-trihydroborane complex, Trihydrido(tetrahydrofuran)boron
• Linear Formula: BH₃OC₄H₈
• CAS Number: 14044-65-6
• Molecular Weight: 85.94
• Beilstein: 3668402
• MDL number: MFCD00012429
• UNSPSC 코드: 12352005
• PubChem Substance ID: 24850560
• NACRES: NA.22

속성

• 포함: <0.005 M sodium borohydride as stabilizer
• Quality Level: 200
• 반응 적합성: reagent type: reductant
• 농도: 1.0 M in THF
• density: 0.898 g/mL at 25 °C
• 작용기: ether
• 저장 온도: 2-8°C
• SMILES string: B.C1CCOC1
• InChI: 1S/C4H8O.BH3/c1-2-4-5-3-1;/h1-4H2;1H3
• InChI key: RMCYTHFAWCWRFA-UHFFFAOYSA-N

설명

일반 설명

Borane tetrahydrofuran complex (BH₃-THF) is widely used as a reducing agent in organic synthesis. It is also used as a reagent in hydroboration reactions.

애플리케이션

New, Safer, NIMBA-Stabilized BH3 THF Solutions

BH₃-THF can be used as a reducing agent for the reduction of various functional groups such as carboxylic acids, aldehydes, ketones, esters, acid chlorides, nitriles, epoxides, amides, lactones, oximes, and imines into corresponding alcohols and amines. Grignard reagents, arylmercury, arylthalium, and allyl and propargyllithium compounds react with BH₃−THF to give organoboranes, which can be oxidized to the corresponding alcohols, phenols, and 1,3-diols.
It can also be used:

• To synthesize the chiral borane catalyst, which is used in the enantioselective halo-aldol reaction.
• To prepare 9-unsubstituted acridines by reduction of corresponding acridones.
• To reduce nylon surface amide groups to secondary amines.

포장

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

법적 정보

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

안전성 정보

• 픽토그램: GHS02,GHS08,GHS05,GHS07
• 신호어: Danger
• 유해 및 위험 성명서: H225,H260,H302,H318,H335,H336,H351
• 예방조치 성명서: P210 - P231 + P232 - P280 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - STOT SE 3 - Water-react 1
• 표적 기관: Central nervous system, Respiratory system
• 보충제 위험성: EUH019
• Storage Class Code: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• WGK: WGK 2
• Flash Point (°F): 1.4 °F - closed cup
• Flash Point (°C): -17 °C - closed cup