추천 제품
product name
(R)-(−)-2-Phenylglycinol, 98%
Quality Level
분석
98%
광학 활성
[α]24/D −31.7°, c = 0.76 in 1 M HCl
광학 순도
ee: 99% (GLC)
반응 적합성
reaction type: solution phase peptide synthesis
mp
75-77 °C (lit.)
응용 분야
peptide synthesis
SMILES string
N[C@@H](CO)c1ccccc1
InChI
1S/C8H11NO/c9-8(6-10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2/t8-/m0/s1
InChI key
IJXJGQCXFSSHNL-QMMMGPOBSA-N
애플리케이션
Amino alcohol used to prepare a chiral imine or oxazolidine from ethyl trifluoropyruvate. These intermediates were then employed in a synthesis of both enantiomers of α-trifluoromethylproline.
Chiral β−amino alcohol used as a synthetic building block.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
이미 열람한 고객
Organic letters, 8(26), 6123-6126 (2006-12-15)
[Structure: see text] A concise synthesis of both enantiomers of alpha-Tfm-proline and (S)-alpha-Tfm-prolinol from ethyl trifluoropyruvate is reported. The key step is a diastereoselective allylation reaction of ethyl trifluoropyruvate and (R)-phenylglycinol-based oxazolidines or imine. The lactone obtained by cyclization of
Tetrahedron Letters, 45, 5287-5287 (2004)
Tetrahedron Letters, 45, 5175-5175 (2004)
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