198005

2-Chloro-1-methylpyridinium iodide

97%

• 동의어(들): Mukaiyama reagent
• 실험식(Hill 표기법): C₆H₇ClIN
• CAS Number: 14338-32-0
• Molecular Weight: 255.48
• Beilstein: 3572320
• EC Number: 238-288-7
• MDL number: MFCD00011984
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24851856
• NACRES: NA.22

속성

• Quality Level: 200
• 분석: 97%
• mp: 200 °C (dec.) (lit.)
• SMILES string: [I-].C[n+]1ccccc1Cl
• InChI: 1S/C6H7ClN.HI/c1-8-5-3-2-4-6(8)7;/h2-5H,1H3;1H/q+1;/p-1
• InChI key: ABFPKTQEQNICFT-UHFFFAOYSA-M

설명

일반 설명

2-Chloro-1-methylpyridinium iodide (Mukaiyama reagent), is a commonly used reagent in organic synthesis for the activation of the hydroxy group of alcohols and carboxylic acids. It is used to synthesize derivatives of esters, lactones, amides, lactams, and ketenes from the corresponding carboxylic acids. It is also used as an efficient coupling reagent in the synthesis of peptides because of its low toxicity, simple reaction conditions, and also less expensive than EDC.

애플리케이션

2-Chloro-1-methylpyridinium iodide (CMPI) can be used as:

• A dehydrating agent for the conversion of various aldoximes to nitriles, and alcohols into alkyl thiocyanates.
• A cross-linking agent to fabricate biodegradable cross-linked hyaluronic acid film and gelatin membranes for biomedical applications.
• A condensing agent to synthesize various β-lactams from β-amino acids.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: dust mask type N95 (US), Eyeshields, Gloves