328820
4-Fluorophenylmagnesium bromide solution
1.0 M in THF
동의어(들):
p-Fluorophenylmagnesium bromide, Bromo(4-fluorophenyl)magnesium, Bromo(p-fluorophenyl)magnesium
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모든 사진(1)
About This Item
Linear Formula:
FC6H4MgBr
CAS Number:
Molecular Weight:
199.30
Beilstein:
636802
MDL number:
UNSPSC 코드:
12352103
PubChem Substance ID:
NACRES:
NA.22
추천 제품
Quality Level
반응 적합성
reaction type: Grignard Reaction
농도
1.0 M in THF
density
1.021 g/mL at 25 °C
작용기
fluoro
SMILES string
Fc1ccc([Mg]Br)cc1
InChI
1S/C6H4F.BrH.Mg/c7-6-4-2-1-3-5-6;;/h2-5H;1H;/q;;+1/p-1
InChI key
QYBFFRXNNFXREA-UHFFFAOYSA-M
유사한 제품을 찾으십니까? 방문 제품 비교 안내
애플리케이션
4-Fluorophenylmagnesium bromide solution (Grignard reagent) can be used as a reagent in the synthesis of:
- Useful key intermediate in the synthesis of paroxetine.
- Arylsulfides via cross-coupling reaction with thiols.
- 4-Arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as androgen receptor antagonists.
- Grignard intermediate for preparing aprepitant.
신호어
Danger
유해 및 위험 성명서
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
표적 기관
Respiratory system
보충제 위험성
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point (°F)
-4.0 °F - closed cup
Flash Point (°C)
-20 °C - closed cup
개인 보호 장비
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
이미 열람한 고객
Design, synthesis, and biological evaluation of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists
Yamamoto S, et al.
Bioorganic & Medicinal Chemistry, 20(7), 2338-2352 (2012)
Enantioselective synthesis of 3-substituted-4-aryl piperidines useful for the preparation of paroxetine
Murthy KS K, et al.
Tetrahedron Letters, 44(28), 5355-5358 (2003)
S K Aggarwal et al.
Clinical chemistry, 40(8), 1494-1502 (1994-08-01)
A stable isotope dilution gas chromatography-mass spectrometry (GC-MS) method is described for the determination of lead (Pb) in urine and whole blood. The use of lithium bis(trifluoroethyl)dithiocarbamate Pb(FDEDTC) as a chelating agent showed strong memory effect, restricting the range of
Jun-Hao Cheng et al.
The Journal of organic chemistry, 77(22), 10369-10374 (2012-10-17)
A convenient one-pot approach for the synthesis of aryl sulfides through the coupling of thiols with Grignard reagents in the presence of N-chlorosuccinimide is described. The sulfenylchlorides were formed when thiols were treated with N-chlorosuccinimide, and the resulting sulfenylchlorides were
Understanding the origin of unusual stepwise hydrogenation kinetics in the synthesis of the 3-(4-fluorophenyl) morpholine moiety of NK1 receptor antagonist aprepitant
Brands KMJ, et al.
Organic Process Research & Development, 10(1), 109-117 (2006)
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