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Merck
모든 사진(1)

문서

359661

Sigma-Aldrich

H-Lys(Boc)-OH

≥95%, for peptide synthesis

동의어(들):

Nε-Boc-L-lysine

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모든 사진(1)

About This Item

Linear Formula:
(CH3)3COCONH(CH2)4CH(NH2)COOH
CAS Number:
2418-95-3
Molecular Weight:
246.30
Beilstein:
2417626
MDL number:
MFCD00037221
UNSPSC 코드:
12352209
PubChem Substance ID:
24862097
NACRES:
NA.22

product name

H-Lys(Boc)-OH, ≥95%

분석

≥95%

형태

powder

광학 활성

[α]20/D +18°, c = 1 in acetic acid

반응 적합성

reaction type: solution phase peptide synthesis

mp

250 °C (dec.) (lit.)

응용 분야

peptide synthesis

저장 온도

2-8°C

SMILES string

CC(C)(C)OC(=O)NCCCC[C@H](N)C(O)=O

InChI

1S/C11H22N2O4/c1-11(2,3)17-10(16)13-7-5-4-6-8(12)9(14)15/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m0/s1

InChI key

VVQIIIAZJXTLRE-QMMMGPOBSA-N

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일반 설명

H-Lys(Boc)-OH also known as Nε-Boc-L-lysine, is commonly used in solution phase peptide synthesis.

애플리케이션

H-Lys(Boc)-OH can be used to prepare pentafluorophenyl esters which further used to synthesize β-peptides.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)

시험 성적서(COA)

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이미 열람한 고객

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Boc-Lys(Fmoc)-OH ≥99.0% (sum of enantiomers, TLC)

Sigma-Aldrich

15435

Boc-Lys(Fmoc)-OH

H-Lys(Alloc)-OH ≥99.0%

Sigma-Aldrich

74218

H-Lys(Alloc)-OH

Boc-D-Lys-OH 98%

Sigma-Aldrich

778222

Boc-D-Lys-OH

Fmoc-Lys-OH Novabiochem®

Sigma-Aldrich

8.52023

Fmoc-Lys-OH

Solution phase synthesis of beta-peptides using micro reactors
P Watts
Tetrahedron, 58, 5427-5439 (2002)
Maria Moccia et al.
International journal of pharmaceutics, 397(1-2), 179-183 (2010-07-06)
A novel nucleic acid compaction device based on a positively-charged alpha,epsilon-poly-l-lysine was realized for the first time. The polycationic peptide was obtained by assembling Fmoc and Boc orthogonally protected l-lysine monomers by solid phase synthesis. The route to the novel
April Case et al.
Analytical biochemistry, 338(2), 237-244 (2005-03-05)
Tissue transglutaminase (TGase) is a Ca(2+)-dependent enzyme that catalyzes cross-linking of intracellular proteins through a mechanism that involves isopeptide bond formation between Gln and Lys residues. In addition to its transamidation activity, TGase can bind guanosine 5'-triphosphate (GTP) and does
Ognyan K Argirov et al.
Biochimica et biophysica acta, 1620(1-3), 235-244 (2003-02-22)
Proteins are subject of posttranslational modification by sugars and their degradation products in vivo. The process is often referred as glycation. L-Dehydroascorbic acid (DHA), an oxidation product of L-ascorbic acid (vitamin C), is known as a potent glycation agent. A
K Itakura et al.
Chemical research in toxicology, 14(5), 473-475 (2001-05-23)
It has been suggested that protein modifications by malondialdehyde (MDA), a major product of lipid peroxidation, contribute to the fluorescence formation of lipofuscin. Although early studies proposed an aminoenimine structure (RNHCH=CHCH=NR) formed from MDA and the epsilon-amino groups of the
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