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Merck
모든 사진(3)

주요 문서

442631

Sigma-Aldrich

Coumarin 6

98%

동의어(들):

3-(2-Benzothiazolyl)-7-(diethylamino)coumarin, 3-(2-Benzothiazolyl)-N,N-diethylumbelliferylamine

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About This Item

실험식(Hill 표기법):
C20H18N2O2S
CAS Number:
Molecular Weight:
350.43
Beilstein:
1085798
EC Number:
MDL number:
UNSPSC 코드:
12352103
PubChem Substance ID:
NACRES:
NA.23

Quality Level

분석

98%

형태

solid

mp

208-210 °C (lit.)

λmax

444 nm

형광

λem 505 nm in ethanol (Lasing peak 534 nm, lasing range 515 - 558 nm (DMSO), pump source XeCl (308 nm))

OLED 기기 성능

ITO/Alq3:Coumarin 6/Mg:Ag

  • Color: green
  • Max. EQE: 2.5 %

SMILES string

CCN(CC)c1ccc2C=C(C(=O)Oc2c1)c3nc4ccccc4s3

InChI

1S/C20H18N2O2S/c1-3-22(4-2)14-10-9-13-11-15(20(23)24-17(13)12-14)19-21-16-7-5-6-8-18(16)25-19/h5-12H,3-4H2,1-2H3

InChI key

VBVAVBCYMYWNOU-UHFFFAOYSA-N

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일반 설명

Coumarin 6 (C6) is a derivative of coumarin with a benzothiazolyl group at the position 3. It emits fluorescence in solid and solution state and is used as fluorescent dye to stain organelles. C6 is majorly used as blue-green spectrum laser dye and is microenvironment sensitive.
Coumarin 6 is a fluorescent dye that belongs to the 7-diethylaminocoumarin series that can be used in a variety of biological activities. It can be used as a dopant that exhibits green light (500 nm) in optoelectronic applications.

애플리케이션

Coumarin 6 dye can be used in the labeling and visualization of polymeric nanoparticles in biological applications, such as oral drug delivery systems for cancer. It can also be used in development of electroluminescent devices such as organic light emitting diodes (OLEDs).
Coumarin 6 has been used as a hydrophobic fluorescent dye
  • in block copolymer (BCP)-based micelle based drug delivery studies in glioma cell lines
  • in combination with flufenamic acid (FA) based nanoprodrug uptake in glioma cells
  • in poly(lactic-co-glycolic acid) (PLGA) based elvitegravir nanoprodrug uptake studies

Laser dye

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Surface modification of indium tin oxide by plasma treatment: An effective method to improve the efficiency, brightness, and reliability of organic light emitting devices.
Wu CC, et al.
Applied Physics Letters, 70(11), 1348-1350 (1997)
Micelle-templated, poly (lactic-co-glycolic acid) nanoparticles for hydrophobic drug delivery
Nabar GM, et al.
International journal of nanomedicine, 13, 351-351 (2018)
Seungil Kim et al.
Journal of biomaterials science. Polymer edition, 28(17), 2082-2099 (2017-08-31)
New amphiphilic PEGylated poly(aspartic acid) graft copolymer (PASP-PEG-Ph) was synthesized as a nanocarrier for intravaginal drug delivery of poorly water-soluble drugs. PASP-PEG-Ph self-assembled into negatively charged spherically shaped nanoparticles in the presence of pH 4.5 and pH 7.0 vaginal fluid
Nanoprodrugs of NSAIDs: Preparation and characterization of flufenamic acid nanoprodrugs
Lee BS, et al.
Journal of Drug Delivery, 2011 (2011)
Synthesis and anti-angiogenesis activity of coumarin derivatives.
Lee S, et al.
Bioorganic & Medicinal Chemistry Letters, 16(17), 4596-4599 (2006)

문서

Micelle formation addresses low solubility in IV drug delivery, overcoming clinical limitations.

Fluorescence quenching microscopy visualizes 2D materials like graphene and MoS2 rapidly, inexpensively, and with high fidelity.

Graphene is the building block for carbon nanomaterials with different dimensionalities.

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