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Merck
모든 사진(2)

주요 문서

499978

Sigma-Aldrich

Benzo[b]thien-2-ylboronic acid

≥95%

동의어(들):

1-Benzothiophene-2-boronic acid, Benzothiophen-2-ylboronic acid, Thianaphthene-2-boronic acid

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About This Item

실험식(Hill 표기법):
C8H7BO2S
CAS Number:
Molecular Weight:
178.02
MDL number:
UNSPSC 코드:
12352103
PubChem Substance ID:
NACRES:
NA.22

Quality Level

분석

≥95%

mp

256-260 °C (lit.)

SMILES string

OB(O)c1cc2ccccc2s1

InChI

1S/C8H7BO2S/c10-9(11)8-5-6-3-1-2-4-7(6)12-8/h1-5,10-11H

InChI key

YNCYPMUJDDXIRH-UHFFFAOYSA-N

애플리케이션

Reactant involved in:
  • PDE4 inhibitors
  • Chemoselective modification of oncolytic adenovirus
  • Synthesis of phosphorescent sensor for quantification of copper(II) ion
  • UV promoted phenanthridine syntheses
  • Preparation of CYP11B1 inhibitors for treatment of cortisol dependent diseases
  • Suzuki-Miyaura cross-coupling reactions

기타 정보

Contains varying amounts of anhydride

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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시험 성적서(COA)

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문서 라이브러리 방문

S A Adediran et al.
Archives of biochemistry and biophysics, 614, 65-71 (2017-01-01)
O-Aryloxycarbonyl hydroxamates have previously been shown to covalently inactivate serine/amine amidohydrolases such as class C β-lactamases and a N-terminal hydrolase, the proteasome. We report here reactions between O-aryloxycarbonyl hydroxamates and another N-terminal hydrolase, penicillin acylase. O-Aryloxycarbonyl hydroxamates, as non-symmetric carbonates
Ju Hyoung Jo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 26(70), 16733-16754 (2020-07-07)
Herein, we report the synthesis, and photochemical and -physical properties, as well as the catalytic performance, of a series of heteroleptic IrIII photosensitizers (IrPSs), [Ir(C^N)2 (N^NAryl )]+ , possessing ancillary ligands that are varied with aryl-substituents on bipyridyl unit [C^N=(2-pyridyl)benzo[b]thiophen-3-yl
Hyomin Jin et al.
Dalton transactions (Cambridge, England : 2003), 48(4), 1467-1476 (2019-01-12)
2-Phenylpyridine- and 2-(benzo[b]thiophen-2-yl)pyridine-based (ppy- and btp-based) o-carboranyl (Car1 and Car2) and their B(CH3)2-C∧N-chelated (Car1B and Car2B) compounds were prepared and fully characterised by multinuclear NMR spectroscopy and elemental analysis. The solid-state structure of Car2B was determined by single-crystal X-ray diffraction
Ramona Iseppi et al.
Microbial drug resistance (Larchmont, N.Y.), 24(8), 1156-1164 (2018-02-17)
We investigated the occurrence of extended-spectrum β-lactamase (ESBL), AmpC, and carbapenemase-producing Gram-negative bacteria isolated from 160 samples of fresh vegetables (n = 80) and ready-to-eat (RTE) prepacked salads (n = 80). Phenotypic and genotypic analyses were carried out on the isolates in terms of
Alberto Venturelli et al.
Journal of medicinal chemistry, 50(23), 5644-5654 (2007-10-25)
Benzo[b]thiophene-2-ylboronic acid, 1, is a 27 nM inhibitor of the class C beta-lactamase AmpC and potentiates the activity of beta-lactam antibiotics in bacteria that express this and related enzymes. As is often true, the potency of compound 1 against the

문서

Suzuki-Miyaura cross-coupling reaction is extensively used in organic chemistry, polymer science, and pharmaceutical industries.

자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..

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