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Merck
모든 사진(2)

문서

529249

Sigma-Aldrich

2-Chloro-1,3-dimethylimidazolinium chloride

for peptide synthesis

동의어(들):

2-Chloro-4,5-dihydro-1,3-dimethyl-1H-imidazolium chloride, DMC

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About This Item

실험식(Hill 표기법):
C5H10Cl2N2
CAS Number:
Molecular Weight:
169.05
MDL number:
UNSPSC 코드:
12352005
PubChem Substance ID:
NACRES:
NA.22

product name

2-Chloro-1,3-dimethylimidazolinium chloride,

형태

crystalline

Quality Level

반응 적합성

reaction type: Coupling Reactions

mp

133-140 °C (lit.)

응용 분야

peptide synthesis

SMILES string

[Cl-].CN1CC[N+](C)=C1Cl

InChI

1S/C5H10ClN2.ClH/c1-7-3-4-8(2)5(7)6;/h3-4H2,1-2H3;1H/q+1;/p-1

InChI key

AEBBXVHGVADBHA-UHFFFAOYSA-M

애플리케이션

Reagent for synthesis of:
Tagged glucose as an intermediate in the synthesis of branched oligosaccharides
Fluorescent chemosensors
1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1
Allosteric glucokinase activators

Reactant for synthesis of:
Organic azides from primary amines

Reagent for aza-Henry reactions
Activating agent in total synthesis of macroviracin A, cycloviracin B1, and cyclic silanes.

픽토그램

Exclamation mark

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

개인 보호 장비

dust mask type N95 (US), Eyeshields, Gloves


시험 성적서(COA)

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문서 라이브러리 방문

Yanzi Gou et al.
Journal of polymer science. Part A, Polymer chemistry, 51(12), 2588-2597 (2013-06-14)
Synthetic glycopolymers are important natural oligosaccharides mimics for many biological applications. To develop glycopolymeric drugs and therapeutic agents, factors that control the receptor-ligand interaction need to be investigated. A library of well-defined glycopolymers has been prepared by the combination of
Journal of Organometallic Chemistry, 686, 175-182 (2003)
Shunya Takahashi et al.
The Journal of organic chemistry, 69(13), 4509-4515 (2004-06-19)
The C(2)-symmetric macrodiolide core 2 of an antiviral agent, macroviracin A (1), was constructed in a single step by the intermolecular macrodimerization of C(22)-hydroxy carboxylic acid 3 with 2-chloro-1,3-dimethylimidazolinium chloride and DMAP in the presence of sodium hydride (NaH). The
Alois Fürstner et al.
Journal of the American Chemical Society, 125(43), 13132-13142 (2003-10-23)
The first total synthesis of the antivirally active glycolipid cycloviracin B(1) (1) is described. The approach is based on a two-directional synthesis strategy which constructs the C(2)()-symmetrical macrodiolide core of the target by an efficient template-directed macrodilactonization reaction promoted by
Shonoi A Ming et al.
Glycobiology, 28(2), 100-107 (2017-12-12)
Neisseria meningitidis Group X is an emerging cause of bacterial meningitis in Sub-Saharan Africa. The capsular polysaccharide of Group X is a homopolymer of N-acetylglucosamine α(1-4) phosphate and is a vaccine target for prevention of disease associated with this meningococcal

문서

N-Acylimidazoles and carbonylimidazoles are reactive intermediates used for amino compound acylation, surpassing DCC as coupling reagents.

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