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Merck
모든 사진(1)

주요 문서

61745

Sigma-Aldrich

N-Lauroylsarcosine sodium salt

≥97.0% (HPLC)

동의어(들):

N-Dodecanoyl-N-methylglycine sodium salt, Sarkosyl NL

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS Number:
Molecular Weight:
293.38
Beilstein:
5322974
EC Number:
MDL number:
UNSPSC 코드:
12161902
PubChem Substance ID:
NACRES:
NA.22

설명

anionic

Quality Level

분석

≥97.0% (HPLC)

양식

powder

분자량

micellar avg mol wt 600

응집 번호

2

기술

protein expression: suitable
protein purification: suitable
protein quantification: suitable

불순물

≤7% water

CMC

14.6 mM (20-25°C)

solubility

H2O: very soluble 293 g/L at 20 °C

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

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일반 설명

N-Lauroylsarcosine is an anionic surfactant with an ability to denature proteins. Due to its microbicidal property, N-lauroylsarcosine is being considered as a potent anti-microbicide in topical formulations, especially against sexually transmitted diseases (STDs).

애플리케이션

N-Lauroylsarcosine sodium salt has been used to study the complexing ability of a novel amphiphilic γ-cyclodextrin with anionic surfactants.

기타 정보

Anionic surfactant.

픽토그램

Skull and crossbonesCorrosion

신호어

Danger

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 2 Inhalation - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flash Point (°F)

512.6 °F - closed cup

Flash Point (°C)

267 °C - closed cup

개인 보호 장비

Eyeshields, Gloves, type N95 (US)


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문서 라이브러리 방문

A facile one-pot synthesis of novel amphiphilic perfluoroalkyl ester functionalized ?-cyclodextrin and complex formation with anionic surfactants.
Lim KT
Journal of Fluorine Chemistry, 127(6), 730-735 (2006)
Jocelyne Piret et al.
Antimicrobial agents and chemotherapy, 46(9), 2933-2942 (2002-08-17)
The mechanisms of herpes simplex virus (HSV) inactivation by sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), two anionic surfactants with protein denaturant potency, have been evaluated in cultured cells. Results showed that pretreatment of HSV type 1 (HSV-1) strain F
S Roy et al.
Antimicrobial agents and chemotherapy, 45(6), 1671-1681 (2001-05-17)
The microbicidal efficacies of two anionic surfactants, sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), were evaluated in cultured cells and in a murine model of herpes simplex type 2 (HSV-2) intravaginal infection. In vitro studies showed that SLS and LS
Gültekin Tamgüney et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(35), 15002-15006 (2009-08-27)
Prions are infectious proteins that cause fatal neurodegenerative diseases. Because astrocytic gliosis marked by the deposition of fibrils composed of GFAP is a prominent feature of prion disease, we asked whether GFAP might be used as a surrogate marker for
Linda A Terry et al.
Veterinary research, 42, 65-65 (2011-05-20)
Classical scrapie is a naturally transmitted prion disease of sheep and goats. Contaminated environments may contribute to the spread of disease and evidence from animal models has implicated urine, blood, saliva, placenta and faeces as possible sources of the infection.

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