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Merck
모든 사진(1)

주요 문서

742678

Sigma-Aldrich

(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol

for Copper-free Click Chemistry

동의어(들):

(1α,8α,9β)-Bicyclo[6.1.0]non-4-yne-9-methanol, endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne, BCN-OH

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About This Item

실험식(Hill 표기법):
C10H14O
CAS Number:
Molecular Weight:
150.22
Beilstein:
21037713
MDL number:
UNSPSC 코드:
12352209
PubChem Substance ID:
NACRES:
NA.22

Quality Level

양식

powder

구성

carbon content, 79.96%
hydrogen content, 9.39%

반응 적합성

reaction type: click chemistry
reagent type: linker

작용기

hydroxyl

저장 온도

−20°C

SMILES string

[H][C@@]12[C@@]([C@H]2CO)([H])CCC#CCC1

InChI

1S/C10H14O/c11-7-10-8-5-3-1-2-4-6-9(8)10/h8-11H,3-7H2/t8-,9+,10-

InChI key

NSVXZMGWYBICRW-ILWJIGKKSA-N

유사한 제품을 찾으십니까? 방문 제품 비교 안내

애플리케이션

Alcohol functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. This strained cyclooctyne will react with azide functionalized compounds or biomolecules without the need for a copper catalyst to result in a stable triazole linkage.

포장

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

이미 열람한 고객

Xifeng Liu et al.
Biomacromolecules, 20(9), 3352-3365 (2019-08-10)
A new PPF-BCN/hyPCL32-N3 injectable system that can be cross-linked by catalyst-free, strain promoted alkyne-azide cycloaddition (SPAAC) click chemistry was developed for tissue engineering applications. The system consisted of two components: PPF-BCN, poly(propylene fumarate) (PPF) functionalized with (1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-ylmethanol (BCN-OH), and hyPCL32-N3
Readily accessible bicyclononynes for bioorthogonal labeling and three-dimensional imaging of living cells.
Jan Dommerholt et al.
Angewandte Chemie (International ed. in English), 49(49), 9422-9425 (2010-09-22)

문서

Copper-free click chemistry is an alternative approach to click chemistry that proceeds at a lower activation barrier and is free of cytotoxic transition metal catalysts.

Explore the principles and applications of click chemistry in drug discovery, highlighting efficient reactions that streamline the synthesis of bioactive compounds.

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