추천 제품
grade
technical
Quality Level
분석
≥80% (T)
형태
solid
반응 적합성
reagent type: cross-linking reagent
저장 온도
−20°C
SMILES string
CC(C)(C)OC(=O)CCOCCOCCOCCN
InChI
1S/C13H27NO5/c1-13(2,3)19-12(15)4-6-16-8-10-18-11-9-17-7-5-14/h4-11,14H2,1-3H3
InChI key
CWFSAZJIJBTKRC-UHFFFAOYSA-N
애플리케이션
tert-Butyl 12-amino-4,7,10-trioxadodecanoate is generally used as a spacer or linker in bioconjugate chemistry. Some of its applications are:
- Synthesis of the tetanus-toxin conjugate of MUC1 glycopeptide antigen, as a potential antitumor vaccine.
- Synthesis of self-assembled monolayer-based surface-enhanced raman scattering (SERS) labels for immuno-SERS microscopy.
- Synthesis of polycationic adamantane-based dendrons for cell imaging.
- Synthesis of phthalocyanine (Pc)-peptide conjugates as potential fluorescence imaging agents for cancers overexpressing epidermal growth factor receptors (EGFR).
기타 정보
Intermediate in the synthesis of a spacer for combinatorial chemistry
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
337.5 °F
Flash Point (°C)
169.7 °C
개인 보호 장비
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
이미 열람한 고객
Towards the Development of Antitumor Vaccines: A Synthetic Conjugate of a Tumor?Associated MUC1 Glycopeptide Antigen and a Tetanus Toxin Epitope.
Angewandte Chemie (International Edition in English), 40(2), 366-369 (2001)
Phthalocyanine?peptide conjugates for epidermal growth factor receptor targeting.
Journal of Medicinal Chemistry, 55(8), 3725-3738 (2012)
Water soluble SERS labels comprising a SAM with dual spacers for controlled bioconjugation.
Physical Chemistry Chemical Physics, 11(34), 7499-7504 (2009)
Polycationic adamantane-based dendrons of different generations display high cellular uptake without triggering cytotoxicity.
Journal of the American Chemical Society, 136(2), 810-819 (2014)
Angewandte Chemie (International Edition in English), 113, 379-379 (2001)
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