C47604

5-Chloroindole

98%

• 실험식(Hill 표기법): C₈H₆ClN
• CAS Number: 17422-32-1
• Molecular Weight: 151.59
• Beilstein: 2651
• EC Number: 241-448-9
• MDL number: MFCD00005672
• UNSPSC 코드: 12352100
• PubChem Substance ID: 24892721
• NACRES: NA.22

속성

• Quality Level: 100
• 분석: 98%
• 형태: crystals
• mp: 69-71 °C (lit.)
• SMILES string: Clc1ccc2[nH]ccc2c1
• InChI: 1S/C8H6ClN/c9-7-1-2-8-6(5-7)3-4-10-8/h1-5,10H
• InChI key: MYTGFBZJLDLWQG-UHFFFAOYSA-N

설명

일반 설명

5-Chloroindole can be synthesized by using 3-chlorobenzaldehyde as starting reagent.

5-Chloroindole is a 5-substituted indole. It undergoes electropolymerization to form a redox-active film consisting of a cyclic trimer and chains of linked cyclic trimer (polymer). It is a potential positive allosteric modulator (PAM) of the 5-HT₃ receptor. It has been reported as strong inhibitor of the copper dissolution in acidic sodium chloride solution. It has been tested as corrosion inhibitor of mild steel in 1N deaerated sulphuric acid. Synthesis of 5-chloroindole, via nitration of indoline has been described.

애플리케이션

5-Chloroindole has been used in the synthesis of 5-chloro-3-indole-N,N- dimethylglyoxalamide and 5-chloro-N,N-dimethyltryptamine. It may be used in the synthesis of dyestuffs in the presence of biocatalysts (Escherichia coli expressing multicomponent phenol hydroxylase (mPH) isolated from Pseudomonas sp. strains KL33 and KL28).

5-Chloroindole has been used to study the biotransformation of substituted indoles to indican derivatives in the tissue cultures of Polygonum tinctorium. It may be employed as a monomer in the preparation of redox-active film made up of a cyclic trimer and chains of linked cyclic trimer (polymer).

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• 개인 보호 장비: Eyeshields, Gloves, type N95 (US)