H8378
D-α-Hydroxyglutaric acid disodium salt
≥95% (GC), cell analysisfor peptide synthesis
동의어(들):
(R)-2-Hydroxypentanedioic acid disodium salt, Disodium (R)-2-hydroxyglutarate
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모든 사진(3)
About This Item
Linear Formula:
C5H6O5Na2
CAS Number:
Molecular Weight:
192.08
Beilstein:
5318041
MDL number:
UNSPSC 코드:
12352106
PubChem Substance ID:
NACRES:
NA.22
추천 제품
제품명
D-α-Hydroxyglutaric acid disodium salt, ≥95% (GC)
Quality Level
분석
≥95% (GC)
양식
powder
색상
white to off-white
응용 분야
cell analysis
peptide synthesis
저장 온도
−20°C
SMILES string
[Na].O[C@H](CCC(O)=O)C(O)=O
InChI
1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m1../s1
InChI key
DZHFTEDSQFPDPP-HWYNEVGZSA-L
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애플리케이션
D-α-Hydroxyglutaric acid disodium salt can be used as a reagent in peptide synthesis.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
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시험 성적서(COA)
Lot/Batch Number
이미 열람한 고객
M Hans et al.
European journal of biochemistry, 265(1), 404-414 (1999-09-22)
Component D (HgdAB) of 2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum was purified to homogeneity. It is able to use component A from Acidaminococcus fermentans (HgdC) to initiate catalysis together with ATP, Mg2+ and a strong reducing agent such as Ti(III)citrate. Component
Shan Jin et al.
Nature communications, 14(1), 6638-6638 (2023-10-21)
Mammalian lactate dehydrogenase D (LDHD) catalyzes the oxidation of D-lactate to pyruvate. LDHD mutations identified in patients with D-lactic acidosis lead to deficient LDHD activity. Here, we perform a systematic biochemical study of mouse LDHD (mLDHD) and determine the crystal
Postoperative risk of IDH mutant glioma-associated seizures and their potential management with IDH mutant inhibitors.
Drumm, et al.
The Journal of Clinical Investigation (2023)
The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells.
Liu Y, Gilbert MR, Kyprianou N, et al.
Acta Neuropathologica, 128(5), 723-732 (2014)
Huan Wang et al.
International journal of cancer, 148(7), 1743-1755 (2020-12-16)
Metabolism reprograming is a hallmark of cancer and plays an important role in tumor progression. The aberrant metabolism in renal cell carcinoma (RCC) leads to accumulation of the oncometabolite L-2-hydroxyglurate (L-2HG). L-2HG has been reported to inhibit the activity of
프로토콜
We describe here a rapid and sensitive method to separate and measure D-2-OHG and L-2-OHG enantiomers using high-resolution mass spectrometry (HRMS) detection.
Chromatograms
application for HPLCapplication for HPLC자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.