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Merck
모든 사진(2)

문서

850469C

Avanti

18:0-20:4 PC

1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine, chloroform

동의어(들):

1-octadecanoyl-2-arachidonyl-sn-glycero-3-phosphocholine; SAPC; PC(18:0/20:4(5Z,8Z,11Z,14Z))

로그인조직 및 계약 가격 보기


About This Item

실험식(Hill 표기법):
C46H84NO8P
CAS Number:
Molecular Weight:
810.13
UNSPSC 코드:
51191904
NACRES:
NA.25

분석

>99% (TLC)

형태

liquid

포장

pkg of 1 × 2.5 mL (850469C-25mg)
pkg of 2 × 4 mL (850469C-200mg)

제조업체/상표

Avanti Research - A Croda Brand 850469C

농도

10 mg/mL (850469C-25mg)
25 mg/mL (850469C-200mg)

지질 유형

phospholipids
cardiolipins

배송 상태

dry ice

저장 온도

−20°C

InChI

1S/C46H84NO8P/c1-6-8-10-12-14-16-18-20-22-23-25-27-29-31-33-35-37-39-46(49)55-44(43-54-56(50,51)53-41-40-47(3,4)5)42-52-45(48)38-36-34-32-30-28-26-24-21-19-17-15-13-11-9-7-2/h14,16,20,22,25,27,31,33,44H,6-13,15,17-19,21,23-24,26,28-30,32,34-43H2,1-5H3/b16-14-,22-20-,27-25-,33-31-/t44-/m1/s1

InChI key

PSVRFUPOQYJOOZ-QNPWAGBNSA-N

일반 설명

18:0-20:4 Phosphatidylcholine (PC) has saturated (18:0) chain in the sn-1 position and unsaturated (20:4) in the sn-2 position. Asymmetric combinations of PC is common among mammalian lipids. PC is a zwitterionic phospholipid. PC is synthesized by Kennedy pathway from choline.

애플리케이션

18:0-20:4 PC is suitable for use:
  • in the preparation of liposomes
  • in the synthesis of diacylglycerol
  • as substrate to determine the activity of phospholipase A2 (PLA2)

생화학적/생리학적 작용

18:0-20:4 phosphatidylcholine (PC) is more prominent in specialized membranes like synaptic vesicles. Phosphatidylcholine is one of the major glycerophospholipids of the eukaryotic membranes. It is essential for maintaining the structure and functions of the membrane. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol.

포장

5 mL Clear Glass Sealed Ampule (850469C-200mg)
5 mL Clear Glass Sealed Ampule (850469C-25mg)

법적 정보

Avanti Research is a trademark of Avanti Polar Lipids, LLC

또한 이 제품과 함께 일반적으로 구입

픽토그램

Skull and crossbonesHealth hazard

신호어

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

표적 기관

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point (°F)

does not flash

Flash Point (°C)

does not flash


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Roles of Trp31 in high membrane binding and proinflammatory activity of human group V phospholipase A2
Han SK, et al.
Journal of biological and chemical chronicles, 274(17), 11881-11888 (1999)
Acyl chain dependence of diacylglycerol activation of protein kinase C activity in vitro
Marignani PA, et al.
Biochemical and Biophysical Research Communications, 225(2), 469-473 (1996)
Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage
Manni M M, et al.
eLife, 7, e34394-e34394 (2018)
The Kennedy pathway?de novo synthesis of phosphatidylethanolamine and phosphatidylcholine
Gibellini F and Smith TK
IUBMB Life, 62(6), 414-428 (2010)
Warren G Hill et al.
American journal of physiology. Cell physiology, 289(1), C33-C41 (2005-02-25)
Caveolae are invaginated membrane structures with high levels of cholesterol, sphingomyelin, and caveolin protein that are predicted to exist as liquid-ordered domains with low water permeability. We isolated a caveolae-enriched membrane fraction without detergents from rat lung and characterized its

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